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Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial Hypertension.
Chen J, Sysol JR, Singla S, Zhao S, Yamamura A, Valdez-Jasso D, Abbasi T, Shioura KM, Sahni S, Reddy V, Sridhar A, Gao H, Torres J, Camp SM, Tang H, Ye SQ, Comhair S, Dweik R, Hassoun P, Yuan JX, Garcia JGN, Machado RF. Chen J, et al. Among authors: sysol jr. Circulation. 2017 Apr 18;135(16):1532-1546. doi: 10.1161/CIRCULATIONAHA.116.024557. Epub 2017 Feb 15. Circulation. 2017. PMID: 28202489 Free PMC article.
Cortactin loss protects against hemin-induced acute lung injury in sickle cell disease.
Jones NM, Sysol JR, Singla S, Smith P, Sandusky GE, Wang H, Natarajan V, Dudek SM, Machado RF. Jones NM, et al. Among authors: sysol jr. Am J Physiol Lung Cell Mol Physiol. 2022 Jun 1;322(6):L890-L897. doi: 10.1152/ajplung.00274.2021. Epub 2022 May 3. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35503995 Free PMC article.
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.
Tang H, Chen J, Fraidenburg DR, Song S, Sysol JR, Drennan AR, Offermanns S, Ye RD, Bonini MG, Minshall RD, Garcia JG, Machado RF, Makino A, Yuan JX. Tang H, et al. Among authors: sysol jr. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15;308(2):L208-20. doi: 10.1152/ajplung.00242.2014. Epub 2014 Nov 21. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 25416384 Free PMC article.
Loss of lung WWOX expression causes neutrophilic inflammation.
Singla S, Chen J, Sethuraman S, Sysol JR, Gampa A, Zhao S, Machado RF. Singla S, et al. Among authors: sysol jr. Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L903-L911. doi: 10.1152/ajplung.00034.2017. Epub 2017 Mar 10. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28283473 Free PMC article.
19 results