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Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research.
Tetteh PW, Kretzschmar K, Begthel H, van den Born M, Korving J, Morsink F, Farin H, van Es JH, Offerhaus GJ, Clevers H. Tetteh PW, et al. Among authors: offerhaus gj. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11859-11864. doi: 10.1073/pnas.1614057113. Epub 2016 Oct 5. Proc Natl Acad Sci U S A. 2016. PMID: 27708166 Free PMC article.
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening.
Driehuis E, van Hoeck A, Moore K, Kolders S, Francies HE, Gulersonmez MC, Stigter ECA, Burgering B, Geurts V, Gracanin A, Bounova G, Morsink FH, Vries R, Boj S, van Es J, Offerhaus GJA, Kranenburg O, Garnett MJ, Wessels L, Cuppen E, Brosens LAA, Clevers H. Driehuis E, et al. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26580-26590. doi: 10.1073/pnas.1911273116. Epub 2019 Dec 9. Proc Natl Acad Sci U S A. 2019. PMID: 31818951 Free PMC article.
SMAD4 immunohistochemistry reflects genetic status in juvenile polyposis syndrome.
Langeveld D, van Hattem WA, de Leng WW, Morsink FH, Ten Kate FJ, Giardiello FM, Offerhaus GJ, Brosens LA. Langeveld D, et al. Among authors: offerhaus gj. Clin Cancer Res. 2010 Aug 15;16(16):4126-34. doi: 10.1158/1078-0432.CCR-10-0168. Epub 2010 Aug 3. Clin Cancer Res. 2010. PMID: 20682711 Free PMC article.
Increased expression of cytoplasmic HuR in familial adenomatous polyposis.
Brosens LA, Keller JJ, Pohjola L, Haglund C, Morsink FH, Iacobuzio-Donahue C, Goggins M, Giardiello FM, Ristimäki A, Offerhaus GJ. Brosens LA, et al. Among authors: offerhaus gj. Cancer Biol Ther. 2008 Mar;7(3):424-7. doi: 10.4161/cbt.7.3.5417. Epub 2007 Dec 13. Cancer Biol Ther. 2008. PMID: 18094611
455 results