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Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.
Todd JA, Evangelou M, Cutler AJ, Pekalski ML, Walker NM, Stevens HE, Porter L, Smyth DJ, Rainbow DB, Ferreira RC, Esposito L, Hunter KM, Loudon K, Irons K, Yang JH, Bell CJ, Schuilenburg H, Heywood J, Challis B, Neupane S, Clarke P, Coleman G, Dawson S, Goymer D, Anselmiova K, Kennet J, Brown J, Caddy SL, Lu J, Greatorex J, Goodfellow I, Wallace C, Tree TI, Evans M, Mander AP, Bond S, Wicker LS, Waldron-Lynch F. Todd JA, et al. Among authors: loudon k. PLoS Med. 2016 Oct 11;13(10):e1002139. doi: 10.1371/journal.pmed.1002139. eCollection 2016 Oct. PLoS Med. 2016. PMID: 27727279 Free PMC article. Clinical Trial.
Resolving the immune landscape of human prostate at a single-cell level in health and cancer.
Tuong ZK, Loudon KW, Berry B, Richoz N, Jones J, Tan X, Nguyen Q, George A, Hori S, Field S, Lynch AG, Kania K, Coupland P, Babbage A, Grenfell R, Barrett T, Warren AY, Gnanapragasam V, Massie C, Clatworthy MR. Tuong ZK, et al. Among authors: loudon kw. Cell Rep. 2021 Dec 21;37(12):110132. doi: 10.1016/j.celrep.2021.110132. Cell Rep. 2021. PMID: 34936871 Free PMC article.
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.
Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ, Ferdinand JR, Collord G, Botting RA, Popescu DM, Loudon KW, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Del Castillo Velasco-Herrera M, Guzzo C, Richoz N, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Maxwell PH, Lindsay S, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Clatworthy M, Behjati S. Young MD, et al. Science. 2018 Aug 10;361(6402):594-599. doi: 10.1126/science.aat1699. Science. 2018. PMID: 30093597 Free PMC article.
Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.
Berry MR, Mathews RJ, Ferdinand JR, Jing C, Loudon KW, Wlodek E, Dennison TW, Kuper C, Neuhofer W, Clatworthy MR. Berry MR, et al. Cell. 2017 Aug 24;170(5):860-874.e19. doi: 10.1016/j.cell.2017.07.022. Epub 2017 Aug 10. Cell. 2017. PMID: 28803730 Free article.
Spatiotemporal immune zonation of the human kidney.
Stewart BJ, Ferdinand JR, Young MD, Mitchell TJ, Loudon KW, Riding AM, Richoz N, Frazer GL, Staniforth JUL, Vieira Braga FA, Botting RA, Popescu DM, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Polanski K, Efremova M, Green K, Del Castillo Velasco-Herrera M, Guzzo C, Collord G, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Lindsay S, Bajenoff M, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Behjati S, Clatworthy MR. Stewart BJ, et al. Among authors: loudon kw. Science. 2019 Sep 27;365(6460):1461-1466. doi: 10.1126/science.aat5031. Science. 2019. PMID: 31604275 Free PMC article.
Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.
Jing C, Castro-Dopico T, Richoz N, Tuong ZK, Ferdinand JR, Lok LSC, Loudon KW, Banham GD, Mathews RJ, Cader Z, Fitzpatrick S, Bashant KR, Kaplan MJ, Kaser A, Johnson RS, Murphy MP, Siegel RM, Clatworthy MR. Jing C, et al. Among authors: loudon kw. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15160-15171. doi: 10.1073/pnas.2000943117. Epub 2020 Jun 15. Proc Natl Acad Sci U S A. 2020. PMID: 32541026 Free PMC article.
Tissue Immunity in the Bladder.
Bowyer GS, Loudon KW, Suchanek O, Clatworthy MR. Bowyer GS, et al. Among authors: loudon kw. Annu Rev Immunol. 2022 Apr 26;40:499-523. doi: 10.1146/annurev-immunol-101220-032117. Annu Rev Immunol. 2022. PMID: 35471839 Review.
Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defence.
Riding AM, Loudon KW, Guo A, Ferdinand JR, Lok LSC, Richoz N, Stewart A, Castro-Dopico T, Tuong ZK, Fiancette R, Bowyer GS, Fleming A, Gillman ES, Suchanek O, Mahbubani KT, Saeb-Parsy K, Withers D, Dougan G, Clare S, Clatworthy MR. Riding AM, et al. Among authors: loudon kw. iScience. 2022 Jun 22;25(7):104660. doi: 10.1016/j.isci.2022.104660. eCollection 2022 Jul 15. iScience. 2022. PMID: 35845169 Free PMC article.
Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer.
Li R, Ferdinand JR, Loudon KW, Bowyer GS, Laidlaw S, Muyas F, Mamanova L, Neves JB, Bolt L, Fasouli ES, Lawson ARJ, Young MD, Hooks Y, Oliver TRW, Butler TM, Armitage JN, Aho T, Riddick ACP, Gnanapragasam V, Welsh SJ, Meyer KB, Warren AY, Tran MGB, Stewart GD, Cortés-Ciriano I, Behjati S, Clatworthy MR, Campbell PJ, Teichmann SA, Mitchell TJ. Li R, et al. Among authors: loudon kw. Cancer Cell. 2022 Dec 12;40(12):1583-1599.e10. doi: 10.1016/j.ccell.2022.11.001. Epub 2022 Nov 23. Cancer Cell. 2022. PMID: 36423636 Free PMC article.
scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservation.
Madissoon E, Wilbrey-Clark A, Miragaia RJ, Saeb-Parsy K, Mahbubani KT, Georgakopoulos N, Harding P, Polanski K, Huang N, Nowicki-Osuch K, Fitzgerald RC, Loudon KW, Ferdinand JR, Clatworthy MR, Tsingene A, van Dongen S, Dabrowska M, Patel M, Stubbington MJT, Teichmann SA, Stegle O, Meyer KB. Madissoon E, et al. Among authors: loudon kw. Genome Biol. 2019 Dec 31;21(1):1. doi: 10.1186/s13059-019-1906-x. Genome Biol. 2019. PMID: 31892341 Free PMC article.
70 results