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Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.
Todd JA, Evangelou M, Cutler AJ, Pekalski ML, Walker NM, Stevens HE, Porter L, Smyth DJ, Rainbow DB, Ferreira RC, Esposito L, Hunter KM, Loudon K, Irons K, Yang JH, Bell CJ, Schuilenburg H, Heywood J, Challis B, Neupane S, Clarke P, Coleman G, Dawson S, Goymer D, Anselmiova K, Kennet J, Brown J, Caddy SL, Lu J, Greatorex J, Goodfellow I, Wallace C, Tree TI, Evans M, Mander AP, Bond S, Wicker LS, Waldron-Lynch F. Todd JA, et al. Among authors: porter l. PLoS Med. 2016 Oct 11;13(10):e1002139. doi: 10.1371/journal.pmed.1002139. eCollection 2016 Oct. PLoS Med. 2016. PMID: 27727279 Free PMC article. Clinical Trial.
The DILfrequency study is an adaptive trial to identify optimal IL-2 dosing in patients with type 1 diabetes.
Seelig E, Howlett J, Porter L, Truman L, Heywood J, Kennet J, Arbon EL, Anselmiova K, Walker NM, Atkar R, Pekalski ML, Rytina E, Evans M, Wicker LS, Todd JA, Mander AP, Bond S, Waldron-Lynch F. Seelig E, et al. Among authors: porter l. JCI Insight. 2018 Oct 4;3(19):e99306. doi: 10.1172/jci.insight.99306. JCI Insight. 2018. PMID: 30282826 Free PMC article. Clinical Trial.
Biomarkers of eosinophilic inflammation in asthma.
Loutsios C, Farahi N, Porter L, Lok LS, Peters AM, Condliffe AM, Chilvers ER. Loutsios C, et al. Among authors: porter l. Expert Rev Respir Med. 2014 Apr;8(2):143-50. doi: 10.1586/17476348.2014.880052. Epub 2014 Jan 27. Expert Rev Respir Med. 2014. PMID: 24460178 Review.
Metabolic Profiling of Human Eosinophils.
Porter L, Toepfner N, Bashant KR, Guck J, Ashcroft M, Farahi N, Chilvers ER. Porter L, et al. Front Immunol. 2018 Jun 21;9:1404. doi: 10.3389/fimmu.2018.01404. eCollection 2018. Front Immunol. 2018. PMID: 30013547 Free PMC article.
Hypoxia upregulates neutrophil degranulation and potential for tissue injury.
Hoenderdos K, Lodge KM, Hirst RA, Chen C, Palazzo SG, Emerenciana A, Summers C, Angyal A, Porter L, Juss JK, O'Callaghan C, Chilvers ER, Condliffe AM. Hoenderdos K, et al. Among authors: porter l. Thorax. 2016 Nov;71(11):1030-1038. doi: 10.1136/thoraxjnl-2015-207604. Epub 2016 Aug 31. Thorax. 2016. PMID: 27581620 Free PMC article.
874 results