Iyer V - Search Results

1

Coupling Data Mining and Laboratory Experiments to Discover Drug Interactions Causing QT Prolongation.

Lorberbaum T, Sampson KJ, Chang JB, Iyer V, Woosley RL, Kass RS, Tatonetti NP. Lorberbaum T, et al. Among authors: iyer v. J Am Coll Cardiol. 2016 Oct 18;68(16):1756-1764. doi: 10.1016/j.jacc.2016.07.761. J Am Coll Cardiol. 2016. PMID: 27737742 Free PMC article.

2

Modeling tissue- and mutation- specific electrophysiological effects in the long QT syndrome: role of the Purkinje fiber.

Iyer V, Sampson KJ, Kass RS. Iyer V, et al. PLoS One. 2014 Jun 3;9(6):e97720. doi: 10.1371/journal.pone.0097720. eCollection 2014. PLoS One. 2014. PMID: 24892747 Free PMC article.

3

Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.

Iyer V, Roman-Campos D, Sampson KJ, Kang G, Fishman GI, Kass RS. Iyer V, et al. Sci Rep. 2015 Aug 20;5:13287. doi: 10.1038/srep13287. Sci Rep. 2015. PMID: 26289036 Free PMC article.

4

A computational model of Purkinje fibre single cell electrophysiology: implications for the long QT syndrome.

Sampson KJ, Iyer V, Marks AR, Kass RS. Sampson KJ, et al. Among authors: iyer v. J Physiol. 2010 Jul 15;588(Pt 14):2643-55. doi: 10.1113/jphysiol.2010.187328. Epub 2010 May 24. J Physiol. 2010. PMID: 20498233 Free PMC article.

5

Molecular Pathophysiology of Congenital Long QT Syndrome.

Bohnen MS, Peng G, Robey SH, Terrenoire C, Iyer V, Sampson KJ, Kass RS. Bohnen MS, et al. Among authors: iyer v. Physiol Rev. 2017 Jan;97(1):89-134. doi: 10.1152/physrev.00008.2016. Physiol Rev. 2017. PMID: 27807201 Free PMC article. Review.

6

KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate.

Osteen JD, Gonzalez C, Sampson KJ, Iyer V, Rebolledo S, Larsson HP, Kass RS. Osteen JD, et al. Among authors: iyer v. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22710-5. doi: 10.1073/pnas.1016300108. Epub 2010 Dec 13. Proc Natl Acad Sci U S A. 2010. PMID: 21149716 Free PMC article.

7

Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry.

Wang K, Terrenoire C, Sampson KJ, Iyer V, Osteen JD, Lu J, Keller G, Kotton DN, Kass RS. Wang K, et al. Among authors: iyer v. J Physiol. 2011 Dec 15;589(Pt 24):6093-104. doi: 10.1113/jphysiol.2011.220863. Epub 2011 Oct 24. J Physiol. 2011. PMID: 22025662 Free PMC article.

8

Novel mechanism of transient outward potassium channel current regulation in the heart: implications for cardiac electrophysiology in health and disease.

Bohnen MS, Iyer V, Sampson KJ, Kass RS. Bohnen MS, et al. Among authors: iyer v. Circ Res. 2015 May 8;116(10):1633-5. doi: 10.1161/CIRCRESAHA.115.306438. Circ Res. 2015. PMID: 25953919 Free PMC article. No abstract available.

9

Pharmacology of the Na_v1.1 domain IV voltage sensor reveals coupling between inactivation gating processes.

Osteen JD, Sampson K, Iyer V, Julius D, Bosmans F. Osteen JD, et al. Among authors: iyer v. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6836-6841. doi: 10.1073/pnas.1621263114. Epub 2017 Jun 12. Proc Natl Acad Sci U S A. 2017. PMID: 28607094 Free PMC article.

10

Unique cardiac Purkinje fiber transient outward current β-subunit composition: a potential molecular link to idiopathic ventricular fibrillation.

Xiao L, Koopmann TT, Ördög B, Postema PG, Verkerk AO, Iyer V, Sampson KJ, Boink GJ, Mamarbachi MA, Varro A, Jordaens L, Res J, Kass RS, Wilde AA, Bezzina CR, Nattel S. Xiao L, et al. Among authors: iyer v. Circ Res. 2013 May 10;112(10):1310-22. doi: 10.1161/CIRCRESAHA.112.300227. Epub 2013 Mar 26. Circ Res. 2013. PMID: 23532596 Free PMC article.

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