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EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells.
Mutz CN, Schwentner R, Aryee DNT, Bouchard EDJ, Mejia EM, Hatch GM, Kauer MO, Katschnig AM, Ban J, Garten A, Alonso J, Banerji V, Kovar H. Mutz CN, et al. Among authors: kauer mo. Oncotarget. 2017 Apr 11;8(15):24679-24693. doi: 10.18632/oncotarget.14976. Oncotarget. 2017. PMID: 28160567 Free PMC article.
A molecular function map of Ewing's sarcoma.
Kauer M, Ban J, Kofler R, Walker B, Davis S, Meltzer P, Kovar H. Kauer M, et al. PLoS One. 2009;4(4):e5415. doi: 10.1371/journal.pone.0005415. Epub 2009 Apr 30. PLoS One. 2009. PMID: 19404404 Free PMC article.
EWS-FLI1 employs an E2F switch to drive target gene expression.
Schwentner R, Papamarkou T, Kauer MO, Stathopoulos V, Yang F, Bilke S, Meltzer PS, Girolami M, Kovar H. Schwentner R, et al. Among authors: kauer mo. Nucleic Acids Res. 2015 Mar 11;43(5):2780-9. doi: 10.1093/nar/gkv123. Epub 2015 Feb 20. Nucleic Acids Res. 2015. PMID: 25712098 Free PMC article.
The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma.
Schwentner R, Herrero-Martin D, Kauer MO, Mutz CN, Katschnig AM, Sienski G, Alonso J, Aryee DN, Kovar H. Schwentner R, et al. Among authors: kauer mo. Oncotarget. 2017 Feb 14;8(7):10980-10993. doi: 10.18632/oncotarget.14091. Oncotarget. 2017. PMID: 28030800 Free PMC article.
Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers.
Tsafou K, Katschnig AM, Radic-Sarikas B, Mutz CN, Iljin K, Schwentner R, Kauer MO, Mühlbacher K, Aryee DNT, Westergaard D, Haapa-Paananen S, Fey V, Superti-Furga G, Toretsky J, Brunak S, Kovar H. Tsafou K, et al. Oncotarget. 2018 Jul 24;9(57):31018-31031. doi: 10.18632/oncotarget.25760. eCollection 2018 Jul 24. Oncotarget. 2018. PMID: 30123424 Free PMC article.
114 results