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Host and Environmental Factors Influencing Individual Human Cytokine Responses.
Ter Horst R, Jaeger M, Smeekens SP, Oosting M, Swertz MA, Li Y, Kumar V, Diavatopoulos DA, Jansen AFM, Lemmers H, Toenhake-Dijkstra H, van Herwaarden AE, Janssen M, van der Molen RG, Joosten I, Sweep FCGJ, Smit JW, Netea-Maier RT, Koenders MMJF, Xavier RJ, van der Meer JWM, Dinarello CA, Pavelka N, Wijmenga C, Notebaart RA, Joosten LAB, Netea MG. Ter Horst R, et al. Among authors: janssen m. Cell. 2016 Nov 3;167(4):1111-1124.e13. doi: 10.1016/j.cell.2016.10.018. Cell. 2016. PMID: 27814508 Free PMC article.
Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout.
Klück V, van Deuren RC, Cavalli G, Shaukat A, Arts P, Cleophas MC, Crișan TO, Tausche AK, Riches P, Dalbeth N, Stamp LK, Hindmarsh JH, Jansen TLTA, Janssen M, Steehouwer M, Lelieveld S, van de Vorst M, Gilissen C, Dagna L, Van de Veerdonk FL, Eisenmesser EZ, Kim S, Merriman TR, Hoischen A, Netea MG, Dinarello CA, Joosten LA. Klück V, et al. Among authors: janssen m. Ann Rheum Dis. 2020 Apr;79(4):536-544. doi: 10.1136/annrheumdis-2019-216233. Epub 2020 Feb 29. Ann Rheum Dis. 2020. PMID: 32114511
Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial.
Klück V, Jansen TLTA, Janssen M, Comarniceanu A, Efdé M, Tengesdal IW, Schraa K, Cleophas MCP, Scribner CL, Skouras DB, Marchetti C, Dinarello CA, Joosten LAB. Klück V, et al. Among authors: janssen m. Lancet Rheumatol. 2020 May;2(5):e270-e280. doi: 10.1016/s2665-9913(20)30065-5. Epub 2020 Apr 8. Lancet Rheumatol. 2020. PMID: 33005902 Free PMC article.
Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout.
McKinney C, Stamp LK, Dalbeth N, Topless RK, Day RO, Kannangara DR, Williams KM, Janssen M, Jansen TL, Joosten LA, Radstake TR, Riches PL, Tausche AK, Lioté F, So A, Merriman TR. McKinney C, et al. Among authors: janssen m. Arthritis Res Ther. 2015 Oct 13;17:288. doi: 10.1186/s13075-015-0802-3. Arthritis Res Ther. 2015. PMID: 26462562 Free PMC article.
The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets.
Rasheed H, McKinney C, Stamp LK, Dalbeth N, Topless RK, Day R, Kannangara D, Williams K, Smith M, Janssen M, Jansen TL, Joosten LA, Radstake TR, Riches PL, Tausche AK, Lioté F, Lu L, Stahl EA, Choi HK, So A, Merriman TR. Rasheed H, et al. Among authors: janssen m. PLoS One. 2016 Jan 25;11(1):e0147939. doi: 10.1371/journal.pone.0147939. eCollection 2016. PLoS One. 2016. PMID: 26808548 Free PMC article.
Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout.
Rasheed H, Phipps-Green AJ, Topless R, Smith MD, Hill C, Lester S, Rischmueller M, Janssen M, Jansen TL, Joosten LA, Radstake TR, Riches PL, Tausche AK, Lioté F, So A, van Rij A, Jones GT, McCormick SP, Harrison AA, Stamp LK, Dalbeth N, Merriman TR. Rasheed H, et al. Among authors: janssen m. Rheumatology (Oxford). 2016 Aug;55(8):1421-30. doi: 10.1093/rheumatology/kew057. Epub 2016 Apr 18. Rheumatology (Oxford). 2016. PMID: 27094595 Free PMC article.
Systematic genetic analysis of early-onset gout: ABCG2 is the only associated locus.
Zaidi F, Narang RK, Phipps-Green A, Gamble GG, Tausche AK, So A, Riches P, Andres M, Perez-Ruiz F, Doherty M, Janssen M, Joosten LAB, Jansen TL, Kurreeman F, Torres RJ, McCarthy GM, Miner JN, Stamp LK, Merriman TR, Dalbeth N. Zaidi F, et al. Among authors: janssen m. Rheumatology (Oxford). 2020 Sep 1;59(9):2544-2549. doi: 10.1093/rheumatology/kez685. Rheumatology (Oxford). 2020. PMID: 31998961
Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout.
Wrigley R, Phipps-Green AJ, Topless RK, Major TJ, Cadzow M, Riches P, Tausche AK, Janssen M, Joosten LAB, Jansen TL, So A, Harré Hindmarsh J, Stamp LK, Dalbeth N, Merriman TR. Wrigley R, et al. Among authors: janssen m. Arthritis Res Ther. 2020 Mar 12;22(1):45. doi: 10.1186/s13075-020-2136-z. Arthritis Res Ther. 2020. PMID: 32164793 Free PMC article.
Association of Gout Polygenic Risk Score With Age at Disease Onset and Tophaceous Disease in European and Polynesian Men With Gout.
Sumpter NA, Takei R, Cadzow M, Topless RKG, Phipps-Green AJ, Murphy R, de Zoysa J, Watson H, Qasim M, Lupi AS, Abhishek A, Andrés M, Crișan TO, Doherty M, Jacobsson L, Janssen M, Jansen TL, Joosten LAB, Kapetanovic M, Lioté F, Matsuo H, McCarthy GM, Perez-Ruiz F, Riches P, Richette P, Roddy E, Stiburkova B, So A, Tausche AK, Torres RJ, Uhlig T, Major TJ, Stamp LK, Dalbeth N, Choi HK, Vazquez AI, Leask MP, Reynolds RJ, Merriman TR. Sumpter NA, et al. Among authors: janssen m. Arthritis Rheumatol. 2023 May;75(5):816-825. doi: 10.1002/art.42393. Epub 2023 Mar 25. Arthritis Rheumatol. 2023. PMID: 36281732
Gout: a clinical syndrome illustrated and discussed.
Bhansing KJ, van Bon L, Janssen M, Radstake TR. Bhansing KJ, et al. Among authors: janssen m. Neth J Med. 2010 Sep;68(9):352-9. Neth J Med. 2010. PMID: 20876915 Free article. Review.
1,631 results