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Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development.
Durek P, Nordström K, Gasparoni G, Salhab A, Kressler C, de Almeida M, Bassler K, Ulas T, Schmidt F, Xiong J, Glažar P, Klironomos F, Sinha A, Kinkley S, Yang X, Arrigoni L, Amirabad AD, Ardakani FB, Feuerbach L, Gorka O, Ebert P, Müller F, Li N, Frischbutter S, Schlickeiser S, Cendon C, Fröhler S, Felder B, Gasparoni N, Imbusch CD, Hutter B, Zipprich G, Tauchmann Y, Reinke S, Wassilew G, Hoffmann U, Richter AS, Sieverling L; DEEP Consortium; Chang HD, Syrbe U, Kalus U, Eils J, Brors B, Manke T, Ruland J, Lengauer T, Rajewsky N, Chen W, Dong J, Sawitzki B, Chung HR, Rosenstiel P, Schulz MH, Schultze JL, Radbruch A, Walter J, Hamann A, Polansky JK. Durek P, et al. Among authors: hoffmann u. Immunity. 2016 Nov 15;45(5):1148-1161. doi: 10.1016/j.immuni.2016.10.022. Immunity. 2016. PMID: 27851915 Free article.
Homeostasis and Durability of T-Cell Memory-The Resting and the Restless T-Cell Memory.
Radbruch A, McGrath MA, Siracusa F, Hoffmann U, Sercan-Alp Ö, Hutloff A, Tokoyoda K, Chang HD, Dong J. Radbruch A, et al. Among authors: hoffmann u. Cold Spring Harb Perspect Biol. 2021 Jul 1;13(7):a038083. doi: 10.1101/cshperspect.a038083. Cold Spring Harb Perspect Biol. 2021. PMID: 33903153 Free PMC article. Review.
A ubiquitous bone marrow reservoir of preexisting SARS-CoV-2-reactive memory CD4+ T lymphocytes in unexposed individuals.
Li J, Reinke S, Shen Y, Schollmeyer L, Liu YC, Wang Z, Hardt S, Hipfl C, Hoffmann U, Frischbutter S, Chang HD, Alexander T, Perka C, Radbruch H, Qin Z, Radbruch A, Dong J. Li J, et al. Among authors: hoffmann u. Front Immunol. 2022 Oct 4;13:1004656. doi: 10.3389/fimmu.2022.1004656. eCollection 2022. Front Immunol. 2022. PMID: 36268016 Free PMC article.
Tolerogenic Immunomodulation by PEGylated Antigenic Peptides.
Pfeil J, Simonetti M, Lauer U, Volkmer R, von Thülen B, Durek P, Krähmer R, Leenders F, Hamann A, Hoffmann U. Pfeil J, et al. Among authors: hoffmann u. Front Immunol. 2020 Oct 9;11:529035. doi: 10.3389/fimmu.2020.529035. eCollection 2020. Front Immunol. 2020. PMID: 33162973 Free PMC article.
Specific microbiota enhances intestinal IgA levels by inducing TGF-β in T follicular helper cells of Peyer's patches in mice.
Beller A, Kruglov A, Durek P, von Goetze V, Werner K, Heinz GA, Ninnemann J, Lehmann K, Maier R, Hoffmann U, Riedel R, Heiking K, Zimmermann J, Siegmund B, Mashreghi MF, Radbruch A, Chang HD. Beller A, et al. Among authors: hoffmann u. Eur J Immunol. 2020 Jun;50(6):783-794. doi: 10.1002/eji.201948474. Epub 2020 Feb 27. Eur J Immunol. 2020. PMID: 32065660 Free article.
miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.
Haftmann C, Stittrich AB, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz GA, Riedel R, Siede J, Lehmann K, Weinberger EE, Zimmel D, Lauer U, Häupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grün JR, Baumgrass R, Matz M, Löhning M, Scheffold A, Wittmann J, Chang HD, Rajewsky N, Jäck HM, Radbruch A, Mashreghi MF. Haftmann C, et al. Among authors: hoffmann u. Eur J Immunol. 2015 Apr;45(4):1192-205. doi: 10.1002/eji.201444633. Epub 2015 Jan 22. Eur J Immunol. 2015. PMID: 25486906 Free PMC article.
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides.
Pfeil J, Simonetti M, Lauer U, von Thülen B, Durek P, Poulsen C, Pawlowska J, Kröger M, Krähmer R, Leenders F, Hoffmann U, Hamann A. Pfeil J, et al. Among authors: hoffmann u. Ther Adv Chronic Dis. 2021 Aug 12;12:20406223211037830. doi: 10.1177/20406223211037830. eCollection 2021. Ther Adv Chronic Dis. 2021. PMID: 34408824 Free PMC article.
Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation.
Yang BH, Hagemann S, Mamareli P, Lauer U, Hoffmann U, Beckstette M, Föhse L, Prinz I, Pezoldt J, Suerbaum S, Sparwasser T, Hamann A, Floess S, Huehn J, Lochner M. Yang BH, et al. Among authors: hoffmann u. Mucosal Immunol. 2016 Mar;9(2):444-57. doi: 10.1038/mi.2015.74. Epub 2015 Aug 26. Mucosal Immunol. 2016. PMID: 26307665 Free article.
1,352 results