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Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development.
Durek P, Nordström K, Gasparoni G, Salhab A, Kressler C, de Almeida M, Bassler K, Ulas T, Schmidt F, Xiong J, Glažar P, Klironomos F, Sinha A, Kinkley S, Yang X, Arrigoni L, Amirabad AD, Ardakani FB, Feuerbach L, Gorka O, Ebert P, Müller F, Li N, Frischbutter S, Schlickeiser S, Cendon C, Fröhler S, Felder B, Gasparoni N, Imbusch CD, Hutter B, Zipprich G, Tauchmann Y, Reinke S, Wassilew G, Hoffmann U, Richter AS, Sieverling L; DEEP Consortium; Chang HD, Syrbe U, Kalus U, Eils J, Brors B, Manke T, Ruland J, Lengauer T, Rajewsky N, Chen W, Dong J, Sawitzki B, Chung HR, Rosenstiel P, Schulz MH, Schultze JL, Radbruch A, Walter J, Hamann A, Polansky JK. Durek P, et al. Among authors: reinke s. Immunity. 2016 Nov 15;45(5):1148-1161. doi: 10.1016/j.immuni.2016.10.022. Immunity. 2016. PMID: 27851915 Free article.
Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory.
Okhrimenko A, Grün JR, Westendorf K, Fang Z, Reinke S, von Roth P, Wassilew G, Kühl AA, Kudernatsch R, Demski S, Scheibenbogen C, Tokoyoda K, McGrath MA, Raftery MJ, Schönrich G, Serra A, Chang HD, Radbruch A, Dong J. Okhrimenko A, et al. Among authors: reinke s. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9229-34. doi: 10.1073/pnas.1318731111. Epub 2014 Jun 10. Proc Natl Acad Sci U S A. 2014. PMID: 24927527 Free PMC article. Clinical Trial.
Resident memory CD4+ T lymphocytes mobilize from bone marrow to contribute to a systemic secondary immune reaction.
Cendón C, Du W, Durek P, Liu YC, Alexander T, Serene L, Yang X, Gasparoni G, Salhab A, Nordström K, Lai T, Schulz AR, Rao A, Heinz GA, Stefanski AL, Claußnitzer A, Siewert K, Dörner T, Chang HD, Volk HD, Romagnani C, Qin Z, Hardt S, Perka C, Reinke S, Walter J, Mashreghi MF, Thurley K, Radbruch A, Dong J. Cendón C, et al. Among authors: reinke s. Eur J Immunol. 2022 May;52(5):737-752. doi: 10.1002/eji.202149726. Epub 2022 Mar 14. Eur J Immunol. 2022. PMID: 35245389 Free article.
A ubiquitous bone marrow reservoir of preexisting SARS-CoV-2-reactive memory CD4+ T lymphocytes in unexposed individuals.
Li J, Reinke S, Shen Y, Schollmeyer L, Liu YC, Wang Z, Hardt S, Hipfl C, Hoffmann U, Frischbutter S, Chang HD, Alexander T, Perka C, Radbruch H, Qin Z, Radbruch A, Dong J. Li J, et al. Among authors: reinke s. Front Immunol. 2022 Oct 4;13:1004656. doi: 10.3389/fimmu.2022.1004656. eCollection 2022. Front Immunol. 2022. PMID: 36268016 Free PMC article.
Terminally differentiated CD8⁺ T cells negatively affect bone regeneration in humans.
Reinke S, Geissler S, Taylor WR, Schmidt-Bleek K, Juelke K, Schwachmeyer V, Dahne M, Hartwig T, Akyüz L, Meisel C, Unterwalder N, Singh NB, Reinke P, Haas NP, Volk HD, Duda GN. Reinke S, et al. Among authors: reinke p. Sci Transl Med. 2013 Mar 20;5(177):177ra36. doi: 10.1126/scitranslmed.3004754. Sci Transl Med. 2013. PMID: 23515078
Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties.
Andrzejewska A, Catar R, Schoon J, Qazi TH, Sass FA, Jacobi D, Blankenstein A, Reinke S, Krüger D, Streitz M, Schlickeiser S, Richter S, Souidi N, Beez C, Kamhieh-Milz J, Krüger U, Zemojtel T, Jürchott K, Strunk D, Reinke P, Duda G, Moll G, Geissler S. Andrzejewska A, et al. Among authors: reinke p, reinke s. Front Immunol. 2019 Nov 8;10:2474. doi: 10.3389/fimmu.2019.02474. eCollection 2019. Front Immunol. 2019. PMID: 31781089 Free PMC article.
CD31+ Cells From Peripheral Blood Facilitate Bone Regeneration in Biologically Impaired Conditions Through Combined Effects on Immunomodulation and Angiogenesis.
Sass FA, Schmidt-Bleek K, Ellinghaus A, Filter S, Rose A, Preininger B, Reinke S, Geissler S, Volk HD, Duda GN, Dienelt A. Sass FA, et al. Among authors: reinke s. J Bone Miner Res. 2017 May;32(5):902-912. doi: 10.1002/jbmr.3062. Epub 2017 Mar 1. J Bone Miner Res. 2017. PMID: 27976803 Free article.
121 results