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Differential Receptor Binding and Regulatory Mechanisms for the Lymphangiogenic Growth Factors Vascular Endothelial Growth Factor (VEGF)-C and -D.
Davydova N, Harris NC, Roufail S, Paquet-Fifield S, Ishaq M, Streltsov VA, Williams SP, Karnezis T, Stacker SA, Achen MG. Davydova N, et al. Among authors: roufail s. J Biol Chem. 2016 Dec 30;291(53):27265-27278. doi: 10.1074/jbc.M116.736801. Epub 2016 Nov 16. J Biol Chem. 2016. PMID: 27852824 Free PMC article.
Viral vascular endothelial growth factors vary extensively in amino acid sequence, receptor-binding specificities, and the ability to induce vascular permeability yet are uniformly active mitogens.
Wise LM, Ueda N, Dryden NH, Fleming SB, Caesar C, Roufail S, Achen MG, Stacker SA, Mercer AA. Wise LM, et al. Among authors: roufail s. J Biol Chem. 2003 Sep 26;278(39):38004-14. doi: 10.1074/jbc.M301194200. Epub 2003 Jul 15. J Biol Chem. 2003. PMID: 12867434 Free article.
Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D.
McColl BK, Baldwin ME, Roufail S, Freeman C, Moritz RL, Simpson RJ, Alitalo K, Stacker SA, Achen MG. McColl BK, et al. Among authors: roufail s. J Exp Med. 2003 Sep 15;198(6):863-8. doi: 10.1084/jem.20030361. Epub 2003 Sep 8. J Exp Med. 2003. PMID: 12963694 Free PMC article.
VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium.
Karnezis T, Shayan R, Caesar C, Roufail S, Harris NC, Ardipradja K, Zhang YF, Williams SP, Farnsworth RH, Chai MG, Rupasinghe TW, Tull DL, Baldwin ME, Sloan EK, Fox SB, Achen MG, Stacker SA. Karnezis T, et al. Among authors: roufail s. Cancer Cell. 2012 Feb 14;21(2):181-95. doi: 10.1016/j.ccr.2011.12.026. Cancer Cell. 2012. PMID: 22340592 Free article.
23 results