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Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme.
Parker LJ, Bocedi A, Ascher DB, Aitken JB, Harris HH, Lo Bello M, Ricci G, Morton CJ, Parker MW. Parker LJ, et al. Among authors: lo bello m. Protein Sci. 2017 Feb;26(2):317-326. doi: 10.1002/pro.3084. Epub 2016 Dec 14. Protein Sci. 2017. PMID: 27863446 Free PMC article.
Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability.
Quesada-Soriano I, Parker LJ, Primavera A, Casas-Solvas JM, Vargas-Berenguel A, Barón C, Morton CJ, Mazzetti AP, Lo Bello M, Parker MW, García-Fuentes L. Quesada-Soriano I, et al. Among authors: lo bello m. Protein Sci. 2009 Dec;18(12):2454-70. doi: 10.1002/pro.253. Protein Sci. 2009. PMID: 19780048 Free PMC article.
Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation.
Parker LJ, Italiano LC, Morton CJ, Hancock NC, Ascher DB, Aitken JB, Harris HH, Campomanes P, Rothlisberger U, De Luca A, Lo Bello M, Ang WH, Dyson PJ, Parker MW. Parker LJ, et al. Among authors: lo bello m. Chemistry. 2011 Jul 4;17(28):7806-16. doi: 10.1002/chem.201100586. Epub 2011 Jun 16. Chemistry. 2011. PMID: 21681839
A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1.
De Luca A, Parker LJ, Ang WH, Rodolfo C, Gabbarini V, Hancock NC, Palone F, Mazzetti AP, Menin L, Morton CJ, Parker MW, Lo Bello M, Dyson PJ. De Luca A, et al. Among authors: lo bello m. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):13943-13951. doi: 10.1073/pnas.1903297116. Epub 2019 Jun 20. Proc Natl Acad Sci U S A. 2019. PMID: 31221747 Free PMC article.
The specific interaction of dinitrosyl-diglutathionyl-iron complex, a natural NO carrier, with the glutathione transferase superfamily: suggestion for an evolutionary pressure in the direction of the storage of nitric oxide.
De Maria F, Pedersen JZ, Caccuri AM, Antonini G, Turella P, Stella L, Lo Bello M, Federici G, Ricci G. De Maria F, et al. Among authors: lo bello m. J Biol Chem. 2003 Oct 24;278(43):42283-93. doi: 10.1074/jbc.M305568200. Epub 2003 Jul 18. J Biol Chem. 2003. PMID: 12871945 Free article.
Glutathione transferase P1-1: self-preservation of an anti-cancer enzyme.
Ricci G, Caccuri AM, Lo Bello M, Parker MW, Nuccetelli M, Turella P, Stella L, Di Iorio EE, Federici G. Ricci G, et al. Among authors: lo bello m. Biochem J. 2003 Nov 15;376(Pt 1):71-6. doi: 10.1042/BJ20030860. Biochem J. 2003. PMID: 12877654 Free PMC article.
Diuretic drug binding to human glutathione transferase P1-1: potential role of Cys-101 revealed in the double mutant C47S/Y108V.
Quesada-Soriano I, Parker LJ, Primavera A, Wielens J, Holien JK, Casas-Solvas JM, Vargas-Berenguel A, Aguilera AM, Nuccetelli M, Mazzetti AP, Lo Bello M, Parker MW, García-Fuentes L. Quesada-Soriano I, et al. Among authors: lo bello m. J Mol Recognit. 2011 Mar-Apr;24(2):220-34. doi: 10.1002/jmr.1040. J Mol Recognit. 2011. PMID: 20540076
82 results