Parker MW - Search Results

1

Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme.

Parker LJ, Bocedi A, Ascher DB, Aitken JB, Harris HH, Lo Bello M, Ricci G, Morton CJ, Parker MW. Parker LJ, et al. Among authors: parker mw. Protein Sci. 2017 Feb;26(2):317-326. doi: 10.1002/pro.3084. Epub 2016 Dec 14. Protein Sci. 2017. PMID: 27863446 Free PMC article.

2

Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 A resolution.

Reinemer P, Dirr HW, Ladenstein R, Huber R, Lo Bello M, Federici G, Parker MW. Reinemer P, et al. Among authors: parker mw. J Mol Biol. 1992 Sep 5;227(1):214-26. doi: 10.1016/0022-2836(92)90692-d. J Mol Biol. 1992. PMID: 1522586

3

Crystallization of glutathione S-transferase from human placenta.

Parker MW, Lo Bello M, Federici G. Parker MW, et al. J Mol Biol. 1990 May 20;213(2):221-2. doi: 10.1016/s0022-2836(05)80183-4. J Mol Biol. 1990. PMID: 2342105

4

Site-directed mutagenesis of human glutathione transferase P1-1. Mutation of Cys-47 induces a positive cooperativity in glutathione transferase P1-1.

Ricci G, Lo Bello M, Caccurri AM, Pastore A, Nuccetelli M, Parker MW, Federici G. Ricci G, et al. Among authors: parker mw. J Biol Chem. 1995 Jan 20;270(3):1243-8. doi: 10.1074/jbc.270.3.1243. J Biol Chem. 1995. PMID: 7836386 Free article.

5

Conformational states of human placental glutathione transferase as probed by limited proteolysis.

Lo Bello M, Pastore A, Petruzzelli R, Parker MW, Wilce MC, Federici G, Ricci G. Lo Bello M, et al. Among authors: parker mw. Biochem Biophys Res Commun. 1993 Jul 30;194(2):804-10. doi: 10.1006/bbrc.1993.1893. Biochem Biophys Res Commun. 1993. PMID: 8343164

6

Peculiar spectroscopic and kinetic properties of Cys-47 in human placental glutathione transferase. Evidence for an atypical thiolate ion pair near the active site.

Lo Bello M, Parker MW, Desideri A, Polticelli F, Falconi M, Del Boccio G, Pennelli A, Federici G, Ricci G. Lo Bello M, et al. Among authors: parker mw. J Biol Chem. 1993 Sep 5;268(25):19033-8. J Biol Chem. 1993. PMID: 8360190 Free article.

7

Structural flexibility modulates the activity of human glutathione transferase P1-1. Influence of a poor co-substrate on dynamics and kinetics of human glutathione transferase.

Caccuri AM, Ascenzi P, Antonini G, Parker MW, Oakley AJ, Chiessi E, Nuccetelli M, Battistoni A, Bellizia A, Ricci G. Caccuri AM, et al. Among authors: parker mw. J Biol Chem. 1996 Jul 5;271(27):16193-8. doi: 10.1074/jbc.271.27.16193. J Biol Chem. 1996. PMID: 8663073 Free article.

8

The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate.

Oakley AJ, Rossjohn J, Lo Bello M, Caccuri AM, Federici G, Parker MW. Oakley AJ, et al. Among authors: parker mw. Biochemistry. 1997 Jan 21;36(3):576-85. doi: 10.1021/bi962316i. Biochemistry. 1997. PMID: 9012673

9

Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme.

Lo Bello M, Oakley AJ, Battistoni A, Mazzetti AP, Nuccetelli M, Mazzarese G, Rossjohn J, Parker MW, Ricci G. Lo Bello M, et al. Among authors: parker mw. Biochemistry. 1997 May 20;36(20):6207-17. doi: 10.1021/bi962813z. Biochemistry. 1997. PMID: 9166793

10

Catalytic mechanism and role of hydroxyl residues in the active site of theta class glutathione S-transferases. Investigation of Ser-9 and Tyr-113 in a glutathione S-transferase from the Australian sheep blowfly, Lucilia cuprina.

Caccuri AM, Antonini G, Nicotra M, Battistoni A, Lo Bello M, Board PG, Parker MW, Ricci G. Caccuri AM, et al. Among authors: parker mw. J Biol Chem. 1997 Nov 21;272(47):29681-6. doi: 10.1074/jbc.272.47.29681. J Biol Chem. 1997. PMID: 9368035 Free article.

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