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Titin-truncating variants affect heart function in disease cohorts and the general population.
Schafer S, de Marvao A, Adami E, Fiedler LR, Ng B, Khin E, Rackham OJ, van Heesch S, Pua CJ, Kui M, Walsh R, Tayal U, Prasad SK, Dawes TJ, Ko NS, Sim D, Chan LL, Chin CW, Mazzarotto F, Barton PJ, Kreuchwig F, de Kleijn DP, Totman T, Biffi C, Tee N, Rueckert D, Schneider V, Faber A, Regitz-Zagrosek V, Seidman JG, Seidman CE, Linke WA, Kovalik JP, O'Regan D, Ware JS, Hubner N, Cook SA. Schafer S, et al. Among authors: chin cw. Nat Genet. 2017 Jan;49(1):46-53. doi: 10.1038/ng.3719. Epub 2016 Nov 21. Nat Genet. 2017. PMID: 27869827 Free PMC article.
Markers of left ventricular decompensation in aortic stenosis.
Chin CW, Vassiliou V, Jenkins WS, Prasad SK, Newby DE, Dweck MR. Chin CW, et al. Expert Rev Cardiovasc Ther. 2014 Jul;12(7):901-12. doi: 10.1586/14779072.2014.923307. Epub 2014 May 28. Expert Rev Cardiovasc Ther. 2014. PMID: 24866867 Review.
Left ventricular hypertrophy with strain and aortic stenosis.
Shah AS, Chin CW, Vassiliou V, Cowell SJ, Doris M, Kwok TC, Semple S, Zamvar V, White AC, McKillop G, Boon NA, Prasad SK, Mills NL, Newby DE, Dweck MR. Shah AS, et al. Among authors: chin cw. Circulation. 2014 Oct 28;130(18):1607-16. doi: 10.1161/CIRCULATIONAHA.114.011085. Epub 2014 Aug 28. Circulation. 2014. PMID: 25170097 Free article.
Myocardial Fibrosis and Cardiac Decompensation in Aortic Stenosis.
Chin CWL, Everett RJ, Kwiecinski J, Vesey AT, Yeung E, Esson G, Jenkins W, Koo M, Mirsadraee S, White AC, Japp AG, Prasad SK, Semple S, Newby DE, Dweck MR. Chin CWL, et al. JACC Cardiovasc Imaging. 2017 Nov;10(11):1320-1333. doi: 10.1016/j.jcmg.2016.10.007. Epub 2016 Dec 21. JACC Cardiovasc Imaging. 2017. PMID: 28017384 Free PMC article.
Novel Index of Maladaptive Myocardial Remodeling in Hypertension.
Goh VJ, Le TT, Bryant J, Wong JI, Su B, Lee CH, Pua CJ, Sim CPY, Ang B, Aw TC, Cook SA, Chin CWL. Goh VJ, et al. Circ Cardiovasc Imaging. 2017 Sep;10(9):e006840. doi: 10.1161/CIRCIMAGING.117.006840. Circ Cardiovasc Imaging. 2017. PMID: 28847911 Free PMC article.
Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients.
Pua CJ, Tham N, Chin CWL, Walsh R, Khor CC, Toepfer CN, Repetti GG, Garfinkel AC, Ewoldt JF, Cloonan P, Chen CS, Lim SQ, Cai J, Loo LY, Kong SC, Chiang CWK, Whiffin N, de Marvao A, Lio PM, Hii AA, Yang CX, Le TT, Bylstra Y, Lim WK, Teo JX, Padilha K, Silva GV, Pan B, Govind R, Buchan RJ, Barton PJR, Tan P, Foo R, Yip JWL, Wong RCC, Chan WX, Pereira AC, Tang HC, Jamuar SS, Ware JS, Seidman JG, Seidman CE, Cook SA. Pua CJ, et al. Circ Genom Precis Med. 2020 Oct;13(5):424-434. doi: 10.1161/CIRCGEN.119.002823. Epub 2020 Aug 20. Circ Genom Precis Med. 2020. PMID: 32815737 Free PMC article.
133 results