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Enhancement of alpha -helicity in the HIV-1 inhibitory peptide DP178 leads to an increased affinity for human monoclonal antibody 2F5 but does not elicit neutralizing responses in vitro. Implications for vaccine design.
Joyce JG, Hurni WM, Bogusky MJ, Garsky VM, Liang X, Citron MP, Danzeisen RC, Miller MD, Shiver JW, Keller PM. Joyce JG, et al. Among authors: citron mp. J Biol Chem. 2002 Nov 29;277(48):45811-20. doi: 10.1074/jbc.M205862200. Epub 2002 Sep 16. J Biol Chem. 2002. PMID: 12237296 Free article.
Characterization of gp120 and its single-chain derivatives, gp120-CD4D12 and gp120-M9: implications for targeting the CD4i epitope in human immunodeficiency virus vaccine design.
Varadarajan R, Sharma D, Chakraborty K, Patel M, Citron M, Sinha P, Yadav R, Rashid U, Kennedy S, Eckert D, Geleziunas R, Bramhill D, Schleif W, Liang X, Shiver J. Varadarajan R, et al. Among authors: citron m. J Virol. 2005 Feb;79(3):1713-23. doi: 10.1128/JVI.79.3.1713-1723.2005. J Virol. 2005. PMID: 15650196 Free PMC article.
Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates.
Bianchi E, Joyce JG, Miller MD, Finnefrock AC, Liang X, Finotto M, Ingallinella P, McKenna P, Citron M, Ottinger E, Hepler RW, Hrin R, Nahas D, Wu C, Montefiori D, Shiver JW, Pessi A, Kim PS. Bianchi E, et al. Among authors: citron m. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10655-60. doi: 10.1073/pnas.1004261107. Epub 2010 May 18. Proc Natl Acad Sci U S A. 2010. PMID: 20483992 Free PMC article.
Small molecule mimetics of an HIV-1 gp41 fusion intermediate as vaccine leads.
Caulfield MJ, Dudkin VY, Ottinger EA, Getty KL, Zuck PD, Kaufhold RM, Hepler RW, McGaughey GB, Citron M, Hrin RC, Wang YJ, Miller MD, Joyce JG. Caulfield MJ, et al. Among authors: citron m. J Biol Chem. 2010 Dec 24;285(52):40604-11. doi: 10.1074/jbc.M110.172197. Epub 2010 Oct 13. J Biol Chem. 2010. PMID: 20943652 Free PMC article.
437 results