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Ex vivo pleural effusion cultures to study chimeric antigen receptor T cell cytotoxicity in an immunocompetent environment.
Cell Rep Methods. 2023 Nov 20;3(11):100622. doi: 10.1016/j.crmeth.2023.100622. Epub 2023 Oct 23.
Cell Rep Methods. 2023.
PMID: 37875122
Free PMC article.
Comparative analysis of assays to measure CAR T-cell-mediated cytotoxicity.
Kiesgen S, Messinger JC, Chintala NK, Tano Z, Adusumilli PS.
Kiesgen S, et al.
Nat Protoc. 2021 Mar;16(3):1331-1342. doi: 10.1038/s41596-020-00467-0. Epub 2021 Feb 15.
Nat Protoc. 2021.
PMID: 33589826
Free PMC article.
Review.
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Chimeric Antigen Receptor (CAR) T-Cell Therapy for Thoracic Malignancies.
Kiesgen S, Chicaybam L, Chintala NK, Adusumilli PS.
Kiesgen S, et al.
J Thorac Oncol. 2018 Jan;13(1):16-26. doi: 10.1016/j.jtho.2017.10.001. Epub 2017 Oct 26.
J Thorac Oncol. 2018.
PMID: 29107016
Free PMC article.
Review.
Item in Clipboard
Bypassing nonparallelism of a monoclonal antibody ligand-binding assay by employment of alternative assay formats.
Kiesgen S, Schröder A, Schwarz T, Czupalla O, Braun M, Gnoth MJ, Grudzinska-Goebel J.
Kiesgen S, et al.
Bioanalysis. 2016 Dec;8(24):2581-2593. doi: 10.4155/bio-2016-0076.
Bioanalysis. 2016.
PMID: 27884079
Clinical Trial.
Item in Clipboard
A Humanized Anti-CD22-Onconase Antibody-Drug Conjugate Mediates Highly Potent Destruction of Targeted Tumor Cells.
Weber T, Mavratzas A, Kiesgen S, Haase S, Bötticher B, Exner E, Mier W, Grosse-Hovest L, Jäger D, Arndt MA, Krauss J.
Weber T, et al. Among authors: kiesgen s.
J Immunol Res. 2015;2015:561814. doi: 10.1155/2015/561814. Epub 2015 Oct 28.
J Immunol Res. 2015.
PMID: 26605343
Free PMC article.
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An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo.
Kiesgen S, Arndt MAE, Körber C, Arnold U, Weber T, Halama N, Keller A, Bötticher B, Schlegelmilch A, Liebers N, Cremer M, Herold-Mende C, Dyckhoff G, Federspil PA, Jensen AD, Jäger D, Kontermann RE, Mier W, Krauss J.
Kiesgen S, et al.
Cancer Lett. 2015 Feb 1;357(1):364-373. doi: 10.1016/j.canlet.2014.11.054. Epub 2014 Nov 27.
Cancer Lett. 2015.
PMID: 25434798
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A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor.
Kiesgen S, Liebers N, Cremer M, Arnold U, Weber T, Keller A, Herold-Mende C, Dyckhoff G, Jäger D, Kontermann RE, Arndt MA, Krauss J.
Kiesgen S, et al.
Protein Eng Des Sel. 2014 Oct;27(10):331-7. doi: 10.1093/protein/gzu040.
Protein Eng Des Sel. 2014.
PMID: 25301960
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