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Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling.
Marín-Ramos NI, Piñar C, Vázquez-Villa H, Martín-Fontecha M, González Á, Canales Á, Algar S, Mayo PP, Jiménez-Barbero J, Gajate C, Mollinedo F, Pardo L, Ortega-Gutiérrez S, Viso A, López-Rodríguez ML. Marín-Ramos NI, et al. Chemistry. 2017 Jan 31;23(7):1676-1685. doi: 10.1002/chem.201604905. Epub 2016 Dec 27. Chemistry. 2017. PMID: 27885731 Free article.
New inhibitors of angiogenesis with antitumor activity in vivo.
Marín-Ramos NI, Alonso D, Ortega-Gutiérrez S, Ortega-Nogales FJ, Balabasquer M, Vázquez-Villa H, Andradas C, Blasco-Benito S, Pérez-Gómez E, Canales Á, Jiménez-Barbero J, Marquina A, del Prado JM, Sánchez C, Martín-Fontecha M, López-Rodríguez ML. Marín-Ramos NI, et al. J Med Chem. 2015 May 14;58(9):3757-66. doi: 10.1021/jm5019252. Epub 2015 May 4. J Med Chem. 2015. PMID: 25906180
Blocking Ras inhibition as an antitumor strategy.
Marín-Ramos NI, Ortega-Gutiérrez S, López-Rodríguez ML. Marín-Ramos NI, et al. Semin Cancer Biol. 2019 Feb;54:91-100. doi: 10.1016/j.semcancer.2018.01.017. Epub 2018 Feb 2. Semin Cancer Biol. 2019. PMID: 29409706 Review.
A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia.
Marín-Ramos NI, Balabasquer M, Ortega-Nogales FJ, Torrecillas IR, Gil-Ordóñez A, Marcos-Ramiro B, Aguilar-Garrido P, Cushman I, Romero A, Medrano FJ, Gajate C, Mollinedo F, Philips MR, Campillo M, Gallardo M, Martín-Fontecha M, López-Rodríguez ML, Ortega-Gutiérrez S. Marín-Ramos NI, et al. J Med Chem. 2019 Jul 11;62(13):6035-6046. doi: 10.1021/acs.jmedchem.9b00145. Epub 2019 Jun 19. J Med Chem. 2019. PMID: 31181882
Involvement of cannabinoids in cellular proliferation.
López-Rodríguez ML, Viso A, Ortega-Gutiérrez S, Díaz-Laviada I. López-Rodríguez ML, et al. Mini Rev Med Chem. 2005 Jan;5(1):97-106. doi: 10.2174/1389557053402819. Mini Rev Med Chem. 2005. PMID: 15638794 Review.
Development of molecular probes for the human 5-HT(6) receptor.
Vázquez-Villa H, González-Vera JA, Benhamú B, Viso A, Fernández de la Pradilla R, Junquera E, Aicart E, López-Rodríguez ML, Ortega-Gutiérrez S. Vázquez-Villa H, et al. J Med Chem. 2010 Oct 14;53(19):7095-106. doi: 10.1021/jm1007177. J Med Chem. 2010. PMID: 20845907
111 results