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The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation.
Ratner D, Orning MP, Proulx MK, Wang D, Gavrilin MA, Wewers MD, Alnemri ES, Johnson PF, Lee B, Mecsas J, Kayagaki N, Goguen JD, Lien E. Ratner D, et al. Among authors: wang d. PLoS Pathog. 2016 Dec 2;12(12):e1006035. doi: 10.1371/journal.ppat.1006035. eCollection 2016 Dec. PLoS Pathog. 2016. PMID: 27911947 Free PMC article.
Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Ataide MA, Andrade WA, Zamboni DS, Wang D, Souza Mdo C, Franklin BS, Elian S, Martins FS, Pereira D, Reed G, Fitzgerald KA, Golenbock DT, Gazzinelli RT. Ataide MA, et al. Among authors: wang d. PLoS Pathog. 2014 Jan;10(1):e1003885. doi: 10.1371/journal.ppat.1003885. Epub 2014 Jan 16. PLoS Pathog. 2014. PMID: 24453977 Free PMC article. Clinical Trial.
Control of the innate immune response by the mevalonate pathway.
Akula MK, Shi M, Jiang Z, Foster CE, Miao D, Li AS, Zhang X, Gavin RM, Forde SD, Germain G, Carpenter S, Rosadini CV, Gritsman K, Chae JJ, Hampton R, Silverman N, Gravallese EM, Kagan JC, Fitzgerald KA, Kastner DL, Golenbock DT, Bergo MO, Wang D. Akula MK, et al. Among authors: wang d. Nat Immunol. 2016 Aug;17(8):922-9. doi: 10.1038/ni.3487. Epub 2016 Jun 6. Nat Immunol. 2016. PMID: 27270400 Free PMC article.
The Ubiquitin-Modifying Enzyme A20 Terminates C-Type Lectin Receptor Signals and Is a Suppressor of Host Defense against Systemic Fungal Infection.
Liang J, Zhang JJ, Huang HI, Kanayama M, Youssef N, Jin YJ, Reyes EY, Abram CL, Yang S, Lowell CA, Wang D, Shao L, Shinohara ML, Zhang JY, Hammer GE. Liang J, et al. Among authors: wang d. Infect Immun. 2020 Aug 19;88(9):e00048-20. doi: 10.1128/IAI.00048-20. Print 2020 Aug 19. Infect Immun. 2020. PMID: 32540868 Free PMC article.
A binary module for microbiota-mediated regulation of γδ17 cells, hallmarked by microbiota-driven expression of programmed cell death protein 1.
Huang HI, Xue Y, Jewell ML, Tan CY, Theriot B, Aggarwal N, Dockterman J, Lin YD, Schroeder EA, Wang D, Xiong N, Coers J, Shinohara ML, Surana NK, Hammer GE. Huang HI, et al. Among authors: wang d. Cell Rep. 2023 Aug 29;42(8):112951. doi: 10.1016/j.celrep.2023.112951. Epub 2023 Aug 8. Cell Rep. 2023. PMID: 37556321 Free PMC article.
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