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Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1.
Chenge JT, Duyet LV, Swami S, McLean KJ, Kavanagh ME, Coyne AG, Rigby SE, Cheesman MR, Girvan HM, Levy CW, Rupp B, von Kries JP, Abell C, Leys D, Munro AW. Chenge JT, et al. Among authors: mclean kj. J Biol Chem. 2017 Jan 27;292(4):1310-1329. doi: 10.1074/jbc.M116.748822. Epub 2016 Dec 8. J Biol Chem. 2017. PMID: 27932461 Free PMC article.
Crystallization and preliminary crystallographic analysis of a novel cytochrome P450 from Mycobacterium tuberculosis.
Mowat CG, Leys D, McLean KJ, Rivers SL, Richmond A, Munro AW, Ortiz Lombardia M, Alzari PM, Reid GA, Chapman SK, Walkinshaw MD. Mowat CG, et al. Among authors: mclean kj. Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):704-5. doi: 10.1107/s0907444902002676. Epub 2002 Mar 22. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 11914502 Free article.
P450 BM3: the very model of a modern flavocytochrome.
Munro AW, Leys DG, McLean KJ, Marshall KR, Ost TW, Daff S, Miles CS, Chapman SK, Lysek DA, Moser CC, Page CC, Dutton PL. Munro AW, et al. Among authors: mclean kj. Trends Biochem Sci. 2002 May;27(5):250-7. doi: 10.1016/s0968-0004(02)02086-8. Trends Biochem Sci. 2002. PMID: 12076537 Review.
The TB structural genomics consortium: providing a structural foundation for drug discovery.
Goulding CW, Apostol M, Anderson DH, Gill HS, Smith CV, Kuo MR, Yang JK, Waldo GS, Suh SW, Chauhan R, Kale A, Bachhawat N, Mande SC, Johnston JM, Lott JS, Baker EN, Arcus VL, Leys D, McLean KJ, Munro AW, Berendzen J, Sharma V, Park MS, Eisenberg D, Sacchettini J, Alber T, Rupp B, Jacobs W Jr, Terwilliger TC. Goulding CW, et al. Among authors: mclean kj. Curr Drug Targets Infect Disord. 2002 Jun;2(2):121-41. doi: 10.2174/1568005023342551. Curr Drug Targets Infect Disord. 2002. PMID: 12462144 Review.
150 results