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Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Herzig Y, Nevo S, Bornstein C, Brezis MR, Ben-Hur S, Shkedy A, Eisenberg-Bord M, Levi B, Delacher M, Goldfarb Y, David E, Weinberger L, Viukov S, Ben-Dor S, Giraud M, Hanna JH, Breiling A, Lyko F, Amit I, Feuerer M, Abramson J. Herzig Y, et al. Among authors: breiling a. Nat Immunol. 2017 Feb;18(2):161-172. doi: 10.1038/ni.3638. Epub 2016 Dec 12. Nat Immunol. 2017. PMID: 27941786
Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.
Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, Plass C, Feuerer M. Delacher M, et al. Among authors: breiling a. Nat Immunol. 2017 Oct;18(10):1160-1172. doi: 10.1038/ni.3799. Epub 2017 Aug 7. Nat Immunol. 2017. PMID: 28783152 Free PMC article.
Rbpj expression in regulatory T cells is critical for restraining TH2 responses.
Delacher M, Schmidl C, Herzig Y, Breloer M, Hartmann W, Brunk F, Kägebein D, Träger U, Hofer AC, Bittner S, Weichenhan D, Imbusch CD, Hotz-Wagenblatt A, Hielscher T, Breiling A, Federico G, Gröne HJ, Schmid RM, Rehli M, Abramson J, Feuerer M. Delacher M, et al. Among authors: breiling a. Nat Commun. 2019 Apr 8;10(1):1621. doi: 10.1038/s41467-019-09276-w. Nat Commun. 2019. PMID: 30962454 Free PMC article.
Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation.
Wiehle L, Raddatz G, Musch T, Dawlaty MM, Jaenisch R, Lyko F, Breiling A. Wiehle L, et al. Among authors: breiling a. Mol Cell Biol. 2015 Nov 23;36(3):452-61. doi: 10.1128/MCB.00587-15. Print 2016 Feb 1. Mol Cell Biol. 2015. PMID: 26598602 Free PMC article.
Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells.
de Souza Rocha Simonini P, Breiling A, Gupta N, Malekpour M, Youns M, Omranipour R, Malekpour F, Volinia S, Croce CM, Najmabadi H, Diederichs S, Sahin O, Mayer D, Lyko F, Hoheisel JD, Riazalhosseini Y. de Souza Rocha Simonini P, et al. Among authors: breiling a. Cancer Res. 2010 Nov 15;70(22):9175-84. doi: 10.1158/0008-5472.CAN-10-1318. Epub 2010 Oct 26. Cancer Res. 2010. PMID: 20978187
31 results