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CRISPR-Cas9 screening identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer.
Boumelha J, de Castro A, Bah N, Cha H, de Carné Trécesson S, Rana S, Tomaschko M, Anastasiou P, Mugarza E, Moore C, Goldstone R, East P, Litchfield K, Lee SH, Molina-Arcas M, Downward J. Boumelha J, et al. Among authors: litchfield k. Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2627. Online ahead of print. Cancer Res. 2024. PMID: 38635884
The Immunopeptidome from a Genomic Perspective: Establishing the Noncanonical Landscape of MHC Class I-Associated Peptides.
Bedran G, Gasser HC, Weke K, Wang T, Bedran D, Laird A, Battail C, Zanzotto FM, Pesquita C, Axelson H, Rajan A, Harrison DJ, Palkowski A, Pawlik M, Parys M, O'Neill JR, Brennan PM, Symeonides SN, Goodlett DR, Litchfield K, Fahraeus R, Hupp TR, Kote S, Alfaro JA. Bedran G, et al. Among authors: litchfield k. Cancer Immunol Res. 2023 Jun 2;11(6):747-762. doi: 10.1158/2326-6066.CIR-22-0621. Cancer Immunol Res. 2023. PMID: 36961404 Free PMC article.
Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors.
Koster R, Mitra N, D'Andrea K, Vardhanabhuti S, Chung CC, Wang Z, Loren Erickson R, Vaughn DJ, Litchfield K, Rahman N, Greene MH, McGlynn KA, Turnbull C, Chanock SJ, Nathanson KL, Kanetsky PA. Koster R, et al. Among authors: litchfield k. Hum Mol Genet. 2014 Nov 15;23(22):6061-8. doi: 10.1093/hmg/ddu305. Epub 2014 Jun 18. Hum Mol Genet. 2014. PMID: 24943593 Free PMC article.
Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25.
Litchfield K, Sultana R, Renwick A, Dudakia D, Seal S, Ramsay E, Powell S, Elliott A, Warren-Perry M, Eeles R, Peto J, Kote-Jarai Z, Muir K, Nsengimana J; UKTCC; Stratton MR, Easton DF, Bishop DT, Huddart RA, Rahman N, Turnbull C; UKTCC. Litchfield K, et al. Hum Mol Genet. 2015 Feb 15;24(4):1169-76. doi: 10.1093/hmg/ddu511. Epub 2014 Oct 3. Hum Mol Genet. 2015. PMID: 25281660 Free PMC article.
105 results