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Ammonia toxicity: from head to toe?
Dasarathy S, Mookerjee RP, Rackayova V, Rangroo Thrane V, Vairappan B, Ott P, Rose CF. Dasarathy S, et al. Metab Brain Dis. 2017 Apr;32(2):529-538. doi: 10.1007/s11011-016-9938-3. Epub 2016 Dec 24. Metab Brain Dis. 2017. PMID: 28012068 Free PMC article. Review.
Hyperammonemia and proteostasis in cirrhosis.
Dasarathy S, Hatzoglou M. Dasarathy S, et al. Curr Opin Clin Nutr Metab Care. 2018 Jan;21(1):30-36. doi: 10.1097/MCO.0000000000000426. Curr Opin Clin Nutr Metab Care. 2018. PMID: 29035972 Free PMC article. Review.
Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF-κB-mediated mechanism.
Qiu J, Thapaliya S, Runkana A, Yang Y, Tsien C, Mohan ML, Narayanan A, Eghtesad B, Mozdziak PE, McDonald C, Stark GR, Welle S, Naga Prasad SV, Dasarathy S. Qiu J, et al. Among authors: dasarathy s. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18162-7. doi: 10.1073/pnas.1317049110. Epub 2013 Oct 21. Proc Natl Acad Sci U S A. 2013. PMID: 24145431 Free PMC article.
Hyperammonemia results in reduced muscle function independent of muscle mass.
McDaniel J, Davuluri G, Hill EA, Moyer M, Runkana A, Prayson R, van Lunteren E, Dasarathy S. McDaniel J, et al. Among authors: dasarathy s. Am J Physiol Gastrointest Liver Physiol. 2016 Feb 1;310(3):G163-70. doi: 10.1152/ajpgi.00322.2015. Epub 2015 Dec 3. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 26635319 Free PMC article.
Ethanol sensitizes skeletal muscle to ammonia-induced molecular perturbations.
Kant S, Davuluri G, Alchirazi KA, Welch N, Heit C, Kumar A, Gangadhariah M, Kim A, McMullen MR, Willard B, Luse DS, Nagy LE, Vasiliou V, Marini AM, Weiner ID, Dasarathy S. Kant S, et al. Among authors: dasarathy s. J Biol Chem. 2019 May 3;294(18):7231-7244. doi: 10.1074/jbc.RA118.005411. Epub 2019 Mar 14. J Biol Chem. 2019. PMID: 30872403 Free PMC article.
300 results