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Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity.
Lofgren S, Hinchcliff M, Carns M, Wood T, Aren K, Arroyo E, Cheung P, Kuo A, Valenzuela A, Haemel A, Wolters PJ, Gordon J, Spiera R, Assassi S, Boin F, Chung L, Fiorentino D, Utz PJ, Whitfield ML, Khatri P. Lofgren S, et al. Among authors: spiera r. JCI Insight. 2016 Dec 22;1(21):e89073. doi: 10.1172/jci.insight.89073. JCI Insight. 2016. PMID: 28018971 Free PMC article.
Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients.
Rice LM, Padilla CM, McLaughlin SR, Mathes A, Ziemek J, Goummih S, Nakerakanti S, York M, Farina G, Whitfield ML, Spiera RF, Christmann RB, Gordon JK, Weinberg J, Simms RW, Lafyatis R. Rice LM, et al. Among authors: spiera rf. J Clin Invest. 2015 Jul 1;125(7):2795-807. doi: 10.1172/JCI77958. Epub 2015 Jun 22. J Clin Invest. 2015. PMID: 26098215 Free PMC article. Clinical Trial.
A longitudinal biomarker for the extent of skin disease in patients with diffuse cutaneous systemic sclerosis.
Rice LM, Ziemek J, Stratton EA, McLaughlin SR, Padilla CM, Mathes AL, Christmann RB, Stifano G, Browning JL, Whitfield ML, Spiera RF, Gordon JK, Simms RW, Zhang Y, Lafyatis R. Rice LM, et al. Among authors: spiera rf. Arthritis Rheumatol. 2015 Nov;67(11):3004-15. doi: 10.1002/art.39287. Arthritis Rheumatol. 2015. PMID: 26240058 Free PMC article.
198 results