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Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms.
Guo MH, Nandakumar SK, Ulirsch JC, Zekavat SM, Buenrostro JD, Natarajan P, Salem RM, Chiarle R, Mitt M, Kals M, Pärn K, Fischer K, Milani L, Mägi R, Palta P, Gabriel SB, Metspalu A, Lander ES, Kathiresan S, Hirschhorn JN, Esko T, Sankaran VG. Guo MH, et al. Among authors: chiarle r. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E327-E336. doi: 10.1073/pnas.1619052114. Epub 2016 Dec 28. Proc Natl Acad Sci U S A. 2017. PMID: 28031487 Free PMC article.
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
Ludwig LS, Lareau CA, Bao EL, Liu N, Utsugisawa T, Tseng AM, Myers SA, Verboon JM, Ulirsch JC, Luo W, Muus C, Fiorini C, Olive ME, Vockley CM, Munschauer M, Hunter A, Ogura H, Yamamoto T, Inada H, Nakagawa S, Ohzono S, Subramanian V, Chiarle R, Glader B, Carr SA, Aryee MJ, Kundaje A, Orkin SH, Regev A, McCavit TL, Kanno H, Sankaran VG. Ludwig LS, et al. Among authors: chiarle r. Blood. 2022 Apr 21;139(16):2534-2546. doi: 10.1182/blood.2021013753. Blood. 2022. PMID: 35030251 Free PMC article.
Parp3 promotes long-range end joining in murine cells.
Layer JV, Cleary JP, Brown AJ, Stevenson KE, Morrow SN, Van Scoyk A, Blasco RB, Karaca E, Meng FL, Frock RL, Tivey T, Kim S, Fuchs H, Chiarle R, Alt FW, Roberts SA, Weinstock DM, Day TA. Layer JV, et al. Among authors: chiarle r. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10076-10081. doi: 10.1073/pnas.1801591115. Epub 2018 Sep 13. Proc Natl Acad Sci U S A. 2018. PMID: 30213852 Free PMC article.
Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma.
Costa C, Barberis L, Ambrogio C, Manazza AD, Patrucco E, Azzolino O, Neilsen PO, Ciraolo E, Altruda F, Prestwich GD, Chiarle R, Wymann M, Ridley A, Hirsch E. Costa C, et al. Among authors: chiarle r. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14354-9. doi: 10.1073/pnas.0703175104. Epub 2007 Aug 24. Proc Natl Acad Sci U S A. 2007. PMID: 17720808 Free PMC article.
FuseFISH: robust detection of transcribed gene fusions in single cells.
Semrau S, Crosetto N, Bienko M, Boni M, Bernasconi P, Chiarle R, van Oudenaarden A. Semrau S, et al. Among authors: chiarle r. Cell Rep. 2014 Jan 16;6(1):18-23. doi: 10.1016/j.celrep.2013.12.002. Epub 2013 Dec 27. Cell Rep. 2014. PMID: 24373969 Free PMC article.
Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma.
Bersani F, Lingua MF, Morena D, Foglizzo V, Miretti S, Lanzetti L, Carrà G, Morotti A, Ala U, Provero P, Chiarle R, Singer S, Ladanyi M, Tuschl T, Ponzetto C, Taulli R. Bersani F, et al. Among authors: chiarle r. Cancer Res. 2016 Oct 15;76(20):6095-6106. doi: 10.1158/0008-5472.CAN-16-0709. Epub 2016 Aug 28. Cancer Res. 2016. PMID: 27569217 Free PMC article.
156 results