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Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity.
Ghosh A, Smith M, James SE, Davila ML, Velardi E, Argyropoulos KV, Gunset G, Perna F, Kreines FM, Levy ER, Lieberman S, Jay HV, Tuckett AZ, Zakrzewski JL, Tan L, Young LF, Takvorian K, Dudakov JA, Jenq RR, Hanash AM, Motta AC, Murphy GF, Liu C, Schietinger A, Sadelain M, van den Brink MR. Ghosh A, et al. Among authors: jenq rr. Nat Med. 2017 Feb;23(2):242-249. doi: 10.1038/nm.4258. Epub 2017 Jan 9. Nat Med. 2017. PMID: 28067900 Free PMC article.
Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor-induced colitis.
Halsey TM, Thomas AS, Hayase T, Ma W, Abu-Sbeih H, Sun B, Parra ER, Jiang ZD, DuPont HL, Sanchez C, El-Himri R, Brown A, Flores I, McDaniel L, Ortega Turrubiates M, Hensel M, Pham D, Watowich SS, Hayase E, Chang CC, Jenq RR, Wang Y. Halsey TM, et al. Among authors: jenq rr. Sci Transl Med. 2023 Jun 14;15(700):eabq4006. doi: 10.1126/scitranslmed.abq4006. Epub 2023 Jun 14. Sci Transl Med. 2023. PMID: 37315113 Free PMC article.
Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors.
Zakrzewski JL, Suh D, Markley JC, Smith OM, King C, Goldberg GL, Jenq R, Holland AM, Grubin J, Cabrera-Perez J, Brentjens RJ, Lu SX, Rizzuto G, Sant'Angelo DB, Riviere I, Sadelain M, Heller G, Zúñiga-Pflücker JC, Lu C, van den Brink MR. Zakrzewski JL, et al. Nat Biotechnol. 2008 Apr;26(4):453-61. doi: 10.1038/nbt1395. Epub 2008 Mar 30. Nat Biotechnol. 2008. PMID: 18376399 Free PMC article.
Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation.
Jenq RR, King CG, Volk C, Suh D, Smith OM, Rao UK, Yim NL, Holland AM, Lu SX, Zakrzewski JL, Goldberg GL, Diab A, Alpdogan O, Penack O, Na IK, Kappel LW, Wolchok JD, Houghton AN, Perales MA, van den Brink MR. Jenq RR, et al. Blood. 2009 Feb 12;113(7):1574-80. doi: 10.1182/blood-2008-05-155697. Epub 2008 Nov 14. Blood. 2009. PMID: 19011222 Free PMC article.
NOD2 regulates hematopoietic cell function during graft-versus-host disease.
Penack O, Smith OM, Cunningham-Bussel A, Liu X, Rao U, Yim N, Na IK, Holland AM, Ghosh A, Lu SX, Jenq RR, Liu C, Murphy GF, Brandl K, van den Brink MR. Penack O, et al. Among authors: jenq rr. J Exp Med. 2009 Sep 28;206(10):2101-10. doi: 10.1084/jem.20090623. Epub 2009 Sep 8. J Exp Med. 2009. PMID: 19737867 Free PMC article.
Relapse after allogeneic hematopoietic cell therapy.
van den Brink MR, Porter DL, Giralt S, Lu SX, Jenq RR, Hanash A, Bishop MR. van den Brink MR, et al. Among authors: jenq rr. Biol Blood Marrow Transplant. 2010 Jan;16(1 Suppl):S138-45. doi: 10.1016/j.bbmt.2009.10.023. Epub 2009 Oct 24. Biol Blood Marrow Transplant. 2010. PMID: 19857588 Free PMC article. Review.
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease.
Na IK, Lu SX, Yim NL, Goldberg GL, Tsai J, Rao U, Smith OM, King CG, Suh D, Hirschhorn-Cymerman D, Palomba L, Penack O, Holland AM, Jenq RR, Ghosh A, Tran H, Merghoub T, Liu C, Sempowski GD, Ventevogel M, Beauchemin N, van den Brink MR. Na IK, et al. Among authors: jenq rr. J Clin Invest. 2010 Jan;120(1):343-56. doi: 10.1172/JCI39395. Epub 2009 Dec 1. J Clin Invest. 2010. PMID: 19955659 Free PMC article.
Second-line age-adjusted International Prognostic Index in patients with advanced non-Hodgkin lymphoma after T-cell depleted allogeneic hematopoietic SCT.
Perales MA, Jenq R, Goldberg JD, Wilton AS, Lee SS, Castro-Malaspina HR, Hsu K, Papadopoulos EB, van den Brink MR, Boulad F, Kernan NA, Small TN, Wolden S, Collins NH, Chiu M, Heller G, O'Reilly RJ, Kewalramani T, Young JW, Jakubowski AA. Perales MA, et al. Bone Marrow Transplant. 2010 Sep;45(9):1408-16. doi: 10.1038/bmt.2009.371. Epub 2010 Jan 11. Bone Marrow Transplant. 2010. PMID: 20062091 Free PMC article.
140 results