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Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity.
Ghosh A, Smith M, James SE, Davila ML, Velardi E, Argyropoulos KV, Gunset G, Perna F, Kreines FM, Levy ER, Lieberman S, Jay HV, Tuckett AZ, Zakrzewski JL, Tan L, Young LF, Takvorian K, Dudakov JA, Jenq RR, Hanash AM, Motta AC, Murphy GF, Liu C, Schietinger A, Sadelain M, van den Brink MR. Ghosh A, et al. Among authors: liu c. Nat Med. 2017 Feb;23(2):242-249. doi: 10.1038/nm.4258. Epub 2017 Jan 9. Nat Med. 2017. PMID: 28067900 Free PMC article.
Increasing T-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex-mismatched bone marrow transplant model.
Friedman JS, Alpdogan O, van den Brink MR, Liu C, Hurwitz D, Boyd A, Kupper TS, Burakoff SJ. Friedman JS, et al. Among authors: liu c. Biol Blood Marrow Transplant. 2004 Jul;10(7):448-60. doi: 10.1016/j.bbmt.2004.03.005. Biol Blood Marrow Transplant. 2004. PMID: 15205666 Free article.
CCR2 is required for CD8-induced graft-versus-host disease.
Terwey TH, Kim TD, Kochman AA, Hubbard VM, Lu S, Zakrzewski JL, Ramirez-Montagut T, Eng JM, Muriglan SJ, Heller G, Murphy GF, Liu C, Budak-Alpdogan T, Alpdogan O, van den Brink MR. Terwey TH, et al. Among authors: liu c. Blood. 2005 Nov 1;106(9):3322-30. doi: 10.1182/blood-2005-05-1860. Epub 2005 Jul 21. Blood. 2005. PMID: 16037386 Free PMC article.
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