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CCR5+T-bet+FoxP3+ Effector CD4 T Cells Drive Atherosclerosis.
Li J, McArdle S, Gholami A, Kimura T, Wolf D, Gerhardt T, Miller J, Weber C, Ley K. Li J, et al. Among authors: gerhardt t. Circ Res. 2016 May 13;118(10):1540-52. doi: 10.1161/CIRCRESAHA.116.308648. Epub 2016 Mar 28. Circ Res. 2016. PMID: 27021296 Free PMC article.
Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100-Reactive CD4+ T-Regulatory Cells.
Wolf D, Gerhardt T, Winkels H, Michel NA, Pramod AB, Ghosheh Y, Brunel S, Buscher K, Miller J, McArdle S, Baas L, Kobiyama K, Vassallo M, Ehinger E, Dileepan T, Ali A, Schell M, Mikulski Z, Sidler D, Kimura T, Sheng X, Horstmann H, Hansen S, Mitre LS, Stachon P, Hilgendorf I, Gaddis DE, Hedrick C, Benedict CA, Peters B, Zirlik A, Sette A, Ley K. Wolf D, et al. Among authors: gerhardt t. Circulation. 2020 Sep 29;142(13):1279-1293. doi: 10.1161/CIRCULATIONAHA.119.042863. Epub 2020 Jul 24. Circulation. 2020. PMID: 32703007 Free PMC article.
Monocyte trafficking across the vessel wall.
Gerhardt T, Ley K. Gerhardt T, et al. Cardiovasc Res. 2015 Aug 1;107(3):321-30. doi: 10.1093/cvr/cvv147. Epub 2015 May 19. Cardiovasc Res. 2015. PMID: 25990461 Free PMC article. Review.
A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense.
Wolf D, Anto-Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann JD, Lim B, Bäuml M, Marki A, Mauler M, Duerschmied D, Fan Z, Winkels H, Sidler D, Diehl P, Zajonc DM, Hilgendorf I, Stachon P, Marchini T, Willecke F, Schell M, Sommer B, von Zur Muhlen C, Reinöhl J, Gerhardt T, Plow EF, Yakubenko V, Libby P, Bode C, Ley K, Peter K, Zirlik A. Wolf D, et al. Among authors: gerhardt t. Nat Commun. 2018 Feb 6;9(1):525. doi: 10.1038/s41467-018-02896-8. Nat Commun. 2018. PMID: 29410422 Free PMC article.
Immune Mechanisms of Plaque Instability.
Gerhardt T, Haghikia A, Stapmanns P, Leistner DM. Gerhardt T, et al. Front Cardiovasc Med. 2022 Jan 11;8:797046. doi: 10.3389/fcvm.2021.797046. eCollection 2021. Front Cardiovasc Med. 2022. PMID: 35087883 Free PMC article. Review.
Cholesterol crystals at the culprit lesion in patients with acute coronary syndrome are associated with worse cardiovascular outcomes at two years follow up - results from the translational OPTICO-ACS study program.
Nelles G, Abdelwahed YS, Seppelt C, Meteva D, Stähli BE, Rai H, Seegers LM, Sieronski L, Musfeldt J, Gerhardt T, Riedel M, Skurk C, Haghikia A, Sinning D, Dreger H, Knebel F, Trippel TD, Krisper M, Klotsche J, Joner M, Landmesser U, Leistner DM. Nelles G, et al. Among authors: gerhardt t. Int J Cardiol. 2024 Mar 15;399:131665. doi: 10.1016/j.ijcard.2023.131665. Epub 2023 Dec 22. Int J Cardiol. 2024. PMID: 38141724
148 results