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Page 1
Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis.
McDonald OG, Li X, Saunders T, Tryggvadottir R, Mentch SJ, Warmoes MO, Word AE, Carrer A, Salz TH, Natsume S, Stauffer KM, Makohon-Moore A, Zhong Y, Wu H, Wellen KE, Locasale JW, Iacobuzio-Donahue CA, Feinberg AP. McDonald OG, et al. Nat Genet. 2017 Mar;49(3):367-376. doi: 10.1038/ng.3753. Epub 2017 Jan 16. Nat Genet. 2017. PMID: 28092686 Free PMC article.
Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk.
Kaneda A, Wang CJ, Cheong R, Timp W, Onyango P, Wen B, Iacobuzio-Donahue CA, Ohlsson R, Andraos R, Pearson MA, Sharov AA, Longo DL, Ko MS, Levchenko A, Feinberg AP. Kaneda A, et al. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20926-31. doi: 10.1073/pnas.0710359105. Epub 2007 Dec 17. Proc Natl Acad Sci U S A. 2007. PMID: 18087038 Free PMC article.
Cancer gene profiling in pancreatic cancer.
Vilardell F, Iacobuzio-Donahue CA. Vilardell F, et al. Methods Mol Biol. 2010;576:279-92. doi: 10.1007/978-1-59745-545-9_14. Methods Mol Biol. 2010. PMID: 19882267
Distant metastasis occurs late during the genetic evolution of pancreatic cancer.
Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, Kamiyama M, Hruban RH, Eshleman JR, Nowak MA, Velculescu VE, Kinzler KW, Vogelstein B, Iacobuzio-Donahue CA. Yachida S, et al. Nature. 2010 Oct 28;467(7319):1114-7. doi: 10.1038/nature09515. Nature. 2010. PMID: 20981102 Free PMC article.
Genomic and epigenomic integration identifies a prognostic signature in colon cancer.
Yi JM, Dhir M, Van Neste L, Downing SR, Jeschke J, Glöckner SC, de Freitas Calmon M, Hooker CM, Funes JM, Boshoff C, Smits KM, van Engeland M, Weijenberg MP, Iacobuzio-Donahue CA, Herman JG, Schuebel KE, Baylin SB, Ahuja N. Yi JM, et al. Clin Cancer Res. 2011 Mar 15;17(6):1535-45. doi: 10.1158/1078-0432.CCR-10-2509. Epub 2011 Jan 28. Clin Cancer Res. 2011. PMID: 21278247 Free PMC article.
Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors.
Yachida S, Vakiani E, White CM, Zhong Y, Saunders T, Morgan R, de Wilde RF, Maitra A, Hicks J, Demarzo AM, Shi C, Sharma R, Laheru D, Edil BH, Wolfgang CL, Schulick RD, Hruban RH, Tang LH, Klimstra DS, Iacobuzio-Donahue CA. Yachida S, et al. Am J Surg Pathol. 2012 Feb;36(2):173-84. doi: 10.1097/PAS.0b013e3182417d36. Am J Surg Pathol. 2012. PMID: 22251937 Free PMC article.
348 results