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iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-κB and p53.
Nakazawa H, Chang K, Shinozaki S, Yasukawa T, Ishimaru K, Yasuhara S, Yu YM, Martyn JA, Tompkins RG, Shimokado K, Kaneki M. Nakazawa H, et al. Among authors: chang k. PLoS One. 2017 Jan 18;12(1):e0170391. doi: 10.1371/journal.pone.0170391. eCollection 2017. PLoS One. 2017. PMID: 28099528 Free PMC article.
Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65.
Shinozaki S, Chang K, Sakai M, Shimizu N, Yamada M, Tanaka T, Nakazawa H, Ichinose F, Yamada Y, Ishigami A, Ito H, Ouchi Y, Starr ME, Saito H, Shimokado K, Stamler JS, Kaneki M. Shinozaki S, et al. Among authors: chang k. Sci Signal. 2014 Nov 11;7(351):ra106. doi: 10.1126/scisignal.2005375. Sci Signal. 2014. PMID: 25389371 Free PMC article.
Nitrosative stress and pathogenesis of insulin resistance.
Kaneki M, Shimizu N, Yamada D, Chang K. Kaneki M, et al. Among authors: chang k. Antioxid Redox Signal. 2007 Mar;9(3):319-29. doi: 10.1089/ars.2006.1464. Antioxid Redox Signal. 2007. PMID: 17184170 Review.
Farnesyltransferase inhibitor FTI-277 reduces mortality of septic mice along with improved bacterial clearance.
Yang W, Yamada M, Tamura Y, Chang K, Mao J, Zou L, Feng Y, Kida K, Scherrer-Crosbie M, Chao W, Ichinose F, Yu YM, Fischman AJ, Tompkins RG, Yao S, Kaneki M. Yang W, et al. Among authors: chang k. J Pharmacol Exp Ther. 2011 Dec;339(3):832-41. doi: 10.1124/jpet.111.183558. Epub 2011 Aug 26. J Pharmacol Exp Ther. 2011. PMID: 21873557 Free PMC article.
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