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iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-κB and p53.
Nakazawa H, Chang K, Shinozaki S, Yasukawa T, Ishimaru K, Yasuhara S, Yu YM, Martyn JA, Tompkins RG, Shimokado K, Kaneki M. Nakazawa H, et al. Among authors: shimokado k. PLoS One. 2017 Jan 18;12(1):e0170391. doi: 10.1371/journal.pone.0170391. eCollection 2017. PLoS One. 2017. PMID: 28099528 Free PMC article.
Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65.
Shinozaki S, Chang K, Sakai M, Shimizu N, Yamada M, Tanaka T, Nakazawa H, Ichinose F, Yamada Y, Ishigami A, Ito H, Ouchi Y, Starr ME, Saito H, Shimokado K, Stamler JS, Kaneki M. Shinozaki S, et al. Among authors: shimokado k. Sci Signal. 2014 Nov 11;7(351):ra106. doi: 10.1126/scisignal.2005375. Sci Signal. 2014. PMID: 25389371 Free PMC article.
Burn-induced muscle metabolic derangements and mitochondrial dysfunction are associated with activation of HIF-1α and mTORC1: Role of protein farnesylation.
Nakazawa H, Ikeda K, Shinozaki S, Kobayashi M, Ikegami Y, Fu M, Nakamura T, Yasuhara S, Yu YM, Martyn JAJ, Tompkins RG, Shimokado K, Yorozu T, Ito H, Inoue S, Kaneki M. Nakazawa H, et al. Among authors: shimokado k. Sci Rep. 2017 Jul 26;7(1):6618. doi: 10.1038/s41598-017-07011-3. Sci Rep. 2017. PMID: 28747716 Free PMC article.
iNOS inhibits hair regeneration in obese diabetic (ob/ob) mice.
Sasaki M, Shinozaki S, Morinaga H, Kaneki M, Nishimura E, Shimokado K. Sasaki M, et al. Among authors: shimokado k. Biochem Biophys Res Commun. 2018 Jul 2;501(4):893-897. doi: 10.1016/j.bbrc.2018.05.071. Epub 2018 May 18. Biochem Biophys Res Commun. 2018. PMID: 29763605 Free article.
128 results