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Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus.
Werth VP, Fiorentino D, Sullivan BA, Boedigheimer MJ, Chiu K, Wang C, Arnold GE, Damore MA, Bigler J, Welcher AA, Russell CB, Martin DA, Chung JB. Werth VP, et al. Among authors: chung jb. Arthritis Rheumatol. 2017 May;69(5):1028-1034. doi: 10.1002/art.40052. Epub 2017 Mar 31. Arthritis Rheumatol. 2017. PMID: 28118537 Free PMC article. Clinical Trial.
Safety, pharmacokinetics and pharmacodynamics of AMG 811, an anti-interferon-γ monoclonal antibody, in SLE subjects without or with lupus nephritis.
Boedigheimer MJ, Martin DA, Amoura Z, Sánchez-Guerrero J, Romero-Diaz J, Kivitz A, Aranow C, Chan TM, Chong YB, Chiu K, Wang C, Sohn W, Arnold GE, Damore MA, Welcher AA, Sullivan BA, Kotzin BL, Chung JB. Boedigheimer MJ, et al. Among authors: chung jb. Lupus Sci Med. 2017 Sep 14;4(1):e000226. doi: 10.1136/lupus-2017-000226. eCollection 2017. Lupus Sci Med. 2017. PMID: 29018537 Free PMC article.
Brief Report: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multiple-Dose Study to Evaluate AMG 557 in Patients With Systemic Lupus Erythematosus and Active Lupus Arthritis.
Cheng LE, Amoura Z, Cheah B, Hiepe F, Sullivan BA, Zhou L, Arnold GE, Tsuji WH, Merrill JT, Chung JB. Cheng LE, et al. Among authors: chung jb. Arthritis Rheumatol. 2018 Jul;70(7):1071-1076. doi: 10.1002/art.40479. Epub 2018 May 25. Arthritis Rheumatol. 2018. PMID: 29513931 Free PMC article. Clinical Trial.
Blockade of interferon-γ normalizes interferon-regulated gene expression and serum CXCL10 levels in patients with systemic lupus erythematosus.
Welcher AA, Boedigheimer M, Kivitz AJ, Amoura Z, Buyon J, Rudinskaya A, Latinis K, Chiu K, Oliner KS, Damore MA, Arnold GE, Sohn W, Chirmule N, Goyal L, Banfield C, Chung JB. Welcher AA, et al. Among authors: chung jb. Arthritis Rheumatol. 2015 Oct;67(10):2713-22. doi: 10.1002/art.39248. Arthritis Rheumatol. 2015. PMID: 26138472 Free PMC article. Clinical Trial.
Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus.
Sullivan BA, Tsuji W, Kivitz A, Peng J, Arnold GE, Boedigheimer MJ, Chiu K, Green CL, Kaliyaperumal A, Wang C, Ferbas J, Chung JB. Sullivan BA, et al. Among authors: chung jb. Lupus Sci Med. 2016 Apr 8;3(1):e000146. doi: 10.1136/lupus-2016-000146. eCollection 2016. Lupus Sci Med. 2016. PMID: 27099766 Free PMC article.
A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis.
Martin DA, Churchill M, Flores-Suarez L, Cardiel MH, Wallace D, Martin R, Phillips K, Kaine JL, Dong H, Salinger D, Stevens E, Russell CB, Chung JB. Martin DA, et al. Among authors: chung jb. Arthritis Res Ther. 2013 Oct 25;15(5):R164. doi: 10.1186/ar4347. Arthritis Res Ther. 2013. PMID: 24286136 Free PMC article. Clinical Trial.
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Mease PJ, Collier DH, Kricorian G, Chung JB. Mease PJ, et al. Among authors: chung jb. Arthritis Rheumatol. 2020 Jul;72(7):1229-1230. doi: 10.1002/art.41273. Epub 2020 May 28. Arthritis Rheumatol. 2020. PMID: 32266796 No abstract available.
Reply.
Curtis JR, Karis E, Yen PK, Kricorian G, Chung JB. Curtis JR, et al. Among authors: chung jb. Arthritis Rheumatol. 2021 Sep;73(9):1771-1772. doi: 10.1002/art.41718. Epub 2021 Aug 9. Arthritis Rheumatol. 2021. PMID: 33750019 No abstract available.
254 results