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Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.
Ecker S, Chen L, Pancaldi V, Bagger FO, Fernández JM, Carrillo de Santa Pau E, Juan D, Mann AL, Watt S, Casale FP, Sidiropoulos N, Rapin N, Merkel A; BLUEPRINT Consortium; Stunnenberg HG, Stegle O, Frontini M, Downes K, Pastinen T, Kuijpers TW, Rico D, Valencia A, Beck S, Soranzo N, Paul DS. Ecker S, et al. Among authors: beck s. Genome Biol. 2017 Jan 26;18(1):18. doi: 10.1186/s13059-017-1156-8. Genome Biol. 2017. PMID: 28126036 Free PMC article.
From genome to epigenome.
Murrell A, Rakyan VK, Beck S. Murrell A, et al. Among authors: beck s. Hum Mol Genet. 2005 Apr 15;14 Spec No 1:R3-R10. doi: 10.1093/hmg/ddi110. Hum Mol Genet. 2005. PMID: 15809270 Review.
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs).
Rakyan VK, Down TA, Thorne NP, Flicek P, Kulesha E, Gräf S, Tomazou EM, Bäckdahl L, Johnson N, Herberth M, Howe KL, Jackson DK, Miretti MM, Fiegler H, Marioni JC, Birney E, Hubbard TJ, Carter NP, Tavaré S, Beck S. Rakyan VK, et al. Among authors: beck s. Genome Res. 2008 Sep;18(9):1518-29. doi: 10.1101/gr.077479.108. Epub 2008 Jun 24. Genome Res. 2008. PMID: 18577705 Free PMC article.
An epigenetic signature in peripheral blood predicts active ovarian cancer.
Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Gayther SA, Apostolidou S, Jones A, Lechner M, Beck S, Jacobs IJ, Widschwendter M. Teschendorff AE, et al. Among authors: beck s. PLoS One. 2009 Dec 18;4(12):e8274. doi: 10.1371/journal.pone.0008274. PLoS One. 2009. PMID: 20019873 Free PMC article.
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.
Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Weisenberger DJ, Shen H, Campan M, Noushmehr H, Bell CG, Maxwell AP, Savage DA, Mueller-Holzner E, Marth C, Kocjan G, Gayther SA, Jones A, Beck S, Wagner W, Laird PW, Jacobs IJ, Widschwendter M. Teschendorff AE, et al. Among authors: beck s. Genome Res. 2010 Apr;20(4):440-6. doi: 10.1101/gr.103606.109. Epub 2010 Mar 10. Genome Res. 2010. PMID: 20219944 Free PMC article.
1,968 results