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168 results

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Page 1
Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice.
Carrat GR, Hu M, Nguyen-Tu MS, Chabosseau P, Gaulton KJ, van de Bunt M, Siddiq A, Falchi M, Thurner M, Canouil M, Pattou F, Leclerc I, Pullen TJ, Cane MC, Prabhala P, Greenwald W, Schulte A, Marchetti P, Ibberson M, MacDonald PE, Manning Fox JE, Gloyn AL, Froguel P, Solimena M, McCarthy MI, Rutter GA. Carrat GR, et al. Among authors: solimena m. Am J Hum Genet. 2017 Feb 2;100(2):238-256. doi: 10.1016/j.ajhg.2017.01.011. Epub 2017 Jan 26. Am J Hum Genet. 2017. PMID: 28132686 Free PMC article.
The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis.
Carrat GR, Haythorne E, Tomas A, Haataja L, Müller A, Arvan P, Piunti A, Cheng K, Huang M, Pullen TJ, Georgiadou E, Stylianides T, Amirruddin NS, Salem V, Distaso W, Cakebread A, Heesom KJ, Lewis PA, Hodson DJ, Briant LJ, Fung ACH, Sessions RB, Alpy F, Kong APS, Benke PI, Torta F, Teo AKK, Leclerc I, Solimena M, Wigley DB, Rutter GA. Carrat GR, et al. Among authors: solimena m. Mol Metab. 2020 Oct;40:101015. doi: 10.1016/j.molmet.2020.101015. Epub 2020 May 13. Mol Metab. 2020. PMID: 32416313 Free PMC article.
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion.
Hu M, Cebola I, Carrat G, Jiang S, Nawaz S, Khamis A, Canouil M, Froguel P, Schulte A, Solimena M, Ibberson M, Marchetti P, Cardenas-Diaz FL, Gadue PJ, Hastoy B, Almeida-Souza L, McMahon H, Rutter GA. Hu M, et al. Among authors: solimena m. Cell Rep. 2021 Feb 2;34(5):108703. doi: 10.1016/j.celrep.2021.108703. Cell Rep. 2021. PMID: 33535042 Free PMC article.
Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes.
Solimena M, Schulte AM, Marselli L, Ehehalt F, Richter D, Kleeberg M, Mziaut H, Knoch KP, Parnis J, Bugliani M, Siddiq A, Jörns A, Burdet F, Liechti R, Suleiman M, Margerie D, Syed F, Distler M, Grützmann R, Petretto E, Moreno-Moral A, Wegbrod C, Sönmez A, Pfriem K, Friedrich A, Meinel J, Wollheim CB, Baretton GB, Scharfmann R, Nogoceke E, Bonifacio E, Sturm D, Meyer-Puttlitz B, Boggi U, Saeger HD, Filipponi F, Lesche M, Meda P, Dahl A, Wigger L, Xenarios I, Falchi M, Thorens B, Weitz J, Bokvist K, Lenzen S, Rutter GA, Froguel P, von Bülow M, Ibberson M, Marchetti P. Solimena M, et al. Diabetologia. 2018 Mar;61(3):641-657. doi: 10.1007/s00125-017-4500-3. Epub 2017 Nov 28. Diabetologia. 2018. PMID: 29185012 Free PMC article.
Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes.
Khamis A, Canouil M, Siddiq A, Crouch H, Falchi M, Bulow MV, Ehehalt F, Marselli L, Distler M, Richter D, Weitz J, Bokvist K, Xenarios I, Thorens B, Schulte AM, Ibberson M, Bonnefond A, Marchetti P, Solimena M, Froguel P. Khamis A, et al. Among authors: solimena m. Mol Metab. 2019 Jun;24:98-107. doi: 10.1016/j.molmet.2019.03.004. Epub 2019 Mar 18. Mol Metab. 2019. PMID: 30956117 Free PMC article.
Fostering improved human islet research: a European perspective.
Marchetti P, Schulte AM, Marselli L, Schoniger E, Bugliani M, Kramer W, Overbergh L, Ullrich S, Gloyn AL, Ibberson M, Rutter G, Froguel P, Groop L, McCarthy MI, Dotta F, Scharfmann R, Magnan C, Eizirik DL, Mathieu C, Cnop M, Thorens B, Solimena M. Marchetti P, et al. Among authors: solimena m. Diabetologia. 2019 Aug;62(8):1514-1516. doi: 10.1007/s00125-019-4911-4. Epub 2019 Jun 13. Diabetologia. 2019. PMID: 31197398 Free PMC article. No abstract available.
Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes.
Marselli L, Piron A, Suleiman M, Colli ML, Yi X, Khamis A, Carrat GR, Rutter GA, Bugliani M, Giusti L, Ronci M, Ibberson M, Turatsinze JV, Boggi U, De Simone P, De Tata V, Lopes M, Nasteska D, De Luca C, Tesi M, Bosi E, Singh P, Campani D, Schulte AM, Solimena M, Hecht P, Rady B, Bakaj I, Pocai A, Norquay L, Thorens B, Canouil M, Froguel P, Eizirik DL, Cnop M, Marchetti P. Marselli L, et al. Among authors: solimena m. Cell Rep. 2020 Dec 1;33(9):108466. doi: 10.1016/j.celrep.2020.108466. Cell Rep. 2020. PMID: 33264613 Free article.
The Expression of Aldolase B in Islets Is Negatively Associated With Insulin Secretion in Humans.
Gerst F, Jaghutriz BA, Staiger H, Schulte AM, Lorza-Gil E, Kaiser G, Panse M, Haug S, Heni M, Schütz M, Stadion M, Schürmann A, Marzetta F, Ibberson M, Sipos B, Fend F, Fleming T, Nawroth PP, Königsrainer A, Nadalin S, Wagner S, Peter A, Fritsche A, Richter D, Solimena M, Häring HU, Ullrich S, Wagner R. Gerst F, et al. Among authors: solimena m. J Clin Endocrinol Metab. 2018 Dec 1;103(12):4373-4383. doi: 10.1210/jc.2018-00791. J Clin Endocrinol Metab. 2018. PMID: 30202879 Free PMC article.
Every islet matters: improving the impact of human islet research.
Gloyn AL, Ibberson M, Marchetti P, Powers AC, Rorsman P, Sander M, Solimena M. Gloyn AL, et al. Among authors: solimena m. Nat Metab. 2022 Aug;4(8):970-977. doi: 10.1038/s42255-022-00607-8. Epub 2022 Aug 11. Nat Metab. 2022. PMID: 35953581 Free PMC article. Review.
168 results