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Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling.
Adams R, Burnley RJ, Valenzano CR, Qureshi O, Doyle C, Lumb S, Del Carmen Lopez M, Griffin R, McMillan D, Taylor RD, Meier C, Mori P, Griffin LM, Wernery U, Kinne J, Rapecki S, Baker TS, Lawson AD, Wright M, Ettorre A. Adams R, et al. Among authors: burnley rj. Sci Rep. 2017 Jan 30;7:37716. doi: 10.1038/srep37716. Sci Rep. 2017. PMID: 28134246 Free PMC article.
A Structural Study of the Cytoplasmic Chaperone Effect of 14-3-3 Proteins on Ataxin-1.
Leysen S, Burnley RJ, Rodriguez E, Milroy LG, Soini L, Adamski CJ, Nitschke L, Davis R, Obsil T, Brunsveld L, Crabbe T, Zoghbi HY, Ottmann C, Davis JM. Leysen S, et al. Among authors: burnley rj. J Mol Biol. 2021 Sep 17;433(19):167174. doi: 10.1016/j.jmb.2021.167174. Epub 2021 Jul 21. J Mol Biol. 2021. PMID: 34302818 Free PMC article.
Structure of smAKAP and its regulation by PKA-mediated phosphorylation.
Burgers PP, Bruystens J, Burnley RJ, Nikolaev VO, Keshwani M, Wu J, Janssen BJ, Taylor SS, Heck AJ, Scholten A. Burgers PP, et al. Among authors: burnley rj. FEBS J. 2016 Jun;283(11):2132-48. doi: 10.1111/febs.13726. Epub 2016 May 6. FEBS J. 2016. PMID: 27028580 Free PMC article.