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Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia.
J Clin Invest. 2017 Mar 1;127(3):814-829. doi: 10.1172/JCI86154. Epub 2017 Jan 30.
J Clin Invest. 2017.
PMID: 28134622
Free PMC article.
Blood collection, platelet isolation and measurement of platelet count and size in mice-a practical guide.
Aurbach K, Spindler M, Haining EJ, Bender M, Pleines I.
Aurbach K, et al.
Platelets. 2019;30(6):698-707. doi: 10.1080/09537104.2018.1528345. Epub 2018 Oct 22.
Platelets. 2019.
PMID: 30346859
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A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis.
Dütting S, Gaits-Iacovoni F, Stegner D, Popp M, Antkowiak A, van Eeuwijk JMM, Nurden P, Stritt S, Heib T, Aurbach K, Angay O, Cherpokova D, Heinz N, Baig AA, Gorelashvili MG, Gerner F, Heinze KG, Ware J, Krohne G, Ruggeri ZM, Nurden AT, Schulze H, Modlich U, Pleines I, Brakebusch C, Nieswandt B.
Dütting S, et al. Among authors: aurbach k.
Nat Commun. 2017 Jun 15;8:15838. doi: 10.1038/ncomms15838.
Nat Commun. 2017.
PMID: 28643773
Free PMC article.
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Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice.
Englert M, Aurbach K, Becker IC, Gerber A, Heib T, Wackerbarth LM, Kusch C, Mott K, Araujo GHM, Baig AA, Dütting S, Knaus UG, Stigloher C, Schulze H, Nieswandt B, Pleines I, Nagy Z.
Englert M, et al. Among authors: aurbach k.
Blood Adv. 2022 Sep 13;6(17):5184-5197. doi: 10.1182/bloodadvances.2021006545.
Blood Adv. 2022.
PMID: 35819450
Free PMC article.
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Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis.
Geue S, Aurbach K, Manke MC, Manukjan G, Münzer P, Stegner D, Brähler C, Walker-Allgaier B, Märklin M, Borst CE, Quintanilla-Fend L, Rath D, Geisler T, Salih HR, Seizer P, Lang F, Nieswandt B, Gawaz M, Schulze H, Pleines I, Borst O.
Geue S, et al. Among authors: aurbach k.
Blood. 2019 Nov 21;134(21):1847-1858. doi: 10.1182/blood.2019000185.
Blood. 2019.
PMID: 31578203
Free article.
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Actin/microtubule crosstalk during platelet biogenesis in mice is critically regulated by Twinfilin1 and Cofilin1.
Becker IC, Scheller I, Wackerbarth LM, Beck S, Heib T, Aurbach K, Manukjan G, Gross C, Spindler M, Nagy Z, Witke W, Lappalainen P, Bender M, Schulze H, Pleines I, Nieswandt B.
Becker IC, et al. Among authors: aurbach k.
Blood Adv. 2020 May 26;4(10):2124-2134. doi: 10.1182/bloodadvances.2019001303.
Blood Adv. 2020.
PMID: 32407474
Free PMC article.
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CK2β regulates thrombopoiesis and Ca2+-triggered platelet activation in arterial thrombosis.
Münzer P, Walker-Allgaier B, Geue S, Langhauser F, Geuss E, Stegner D, Aurbach K, Semeniak D, Chatterjee M, Gonzalez Menendez I, Märklin M, Quintanilla-Martinez L, Salih HR, Litchfield DW, Buchou T, Kleinschnitz C, Lang F, Nieswandt B, Pleines I, Schulze H, Gawaz M, Borst O.
Münzer P, et al. Among authors: aurbach k.
Blood. 2017 Dec 21;130(25):2774-2785. doi: 10.1182/blood-2017-05-784413. Epub 2017 Sep 19.
Blood. 2017.
PMID: 28928125
Free article.
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Thymosin β4 is essential for thrombus formation by controlling the G-actin/F-actin equilibrium in platelets.
Scheller I, Beck S, Göb V, Gross C, Neagoe RAI, Aurbach K, Bender M, Stegner D, Nagy Z, Nieswandt B.
Scheller I, et al. Among authors: aurbach k.
Haematologica. 2022 Dec 1;107(12):2846-2858. doi: 10.3324/haematol.2021.278537.
Haematologica. 2022.
PMID: 34348450
Free PMC article.
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