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Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing.
Jansen IE, Ye H, Heetveld S, Lechler MC, Michels H, Seinstra RI, Lubbe SJ, Drouet V, Lesage S, Majounie E, Gibbs JR, Nalls MA, Ryten M, Botia JA, Vandrovcova J, Simon-Sanchez J, Castillo-Lizardo M, Rizzu P, Blauwendraat C, Chouhan AK, Li Y, Yogi P, Amin N, van Duijn CM; International Parkinson’s Disease Genetics Consortium (IPGDC); Morris HR, Brice A, Singleton AB, David DC, Nollen EA, Jain S, Shulman JM, Heutink P. Jansen IE, et al. Among authors: david dc. Genome Biol. 2017 Jan 30;18(1):22. doi: 10.1186/s13059-017-1147-9. Genome Biol. 2017. PMID: 28137300 Free PMC article.
Extracellular proteostasis prevents aggregation during pathogenic attack.
Gallotta I, Sandhu A, Peters M, Haslbeck M, Jung R, Agilkaya S, Blersch JL, Rödelsperger C, Röseler W, Huang C, Sommer RJ, David DC. Gallotta I, et al. Among authors: david dc. Nature. 2020 Aug;584(7821):410-414. doi: 10.1038/s41586-020-2461-z. Epub 2020 Jul 8. Nature. 2020. PMID: 32641833
Aging and the aggregating proteome.
David DC. David DC. Front Genet. 2012 Nov 20;3:247. doi: 10.3389/fgene.2012.00247. eCollection 2012. Front Genet. 2012. PMID: 23181070 Free PMC article.
Age-Dependent Protein Aggregation Initiates Amyloid-β Aggregation.
Groh N, Bühler A, Huang C, Li KW, van Nierop P, Smit AB, Fändrich M, Baumann F, David DC. Groh N, et al. Among authors: david dc. Front Aging Neurosci. 2017 May 17;9:138. doi: 10.3389/fnagi.2017.00138. eCollection 2017. Front Aging Neurosci. 2017. PMID: 28567012 Free PMC article.
Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report.
Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J, Jakob U, David DC, Bennett EJ, Bertozzi CR, Sardana R, Eapen VV, Carra S. Cable J, et al. Among authors: david dc. Ann N Y Acad Sci. 2022 Apr;1510(1):79-99. doi: 10.1111/nyas.14745. Epub 2022 Jan 8. Ann N Y Acad Sci. 2022. PMID: 35000205
24 results