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Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay.
Ji J, Zhang Y, Redon CE, Reinhold WC, Chen AP, Fogli LK, Holbeck SL, Parchment RE, Hollingshead M, Tomaszewski JE, Dudon Q, Pommier Y, Doroshow JH, Bonner WM. Ji J, et al. Among authors: bonner wm. PLoS One. 2017 Feb 3;12(2):e0171582. doi: 10.1371/journal.pone.0171582. eCollection 2017. PLoS One. 2017. PMID: 28158293 Free PMC article.
Phase I study of PARP inhibitor ABT-888 in combination with topotecan in adults with refractory solid tumors and lymphomas.
Kummar S, Chen A, Ji J, Zhang Y, Reid JM, Ames M, Jia L, Weil M, Speranza G, Murgo AJ, Kinders R, Wang L, Parchment RE, Carter J, Stotler H, Rubinstein L, Hollingshead M, Melillo G, Pommier Y, Bonner W, Tomaszewski JE, Doroshow JH. Kummar S, et al. Cancer Res. 2011 Sep 1;71(17):5626-34. doi: 10.1158/0008-5472.CAN-11-1227. Epub 2011 Jul 27. Cancer Res. 2011. PMID: 21795476 Free PMC article. Clinical Trial.
Histone H2A variants H2AX and H2AZ.
Redon C, Pilch D, Rogakou E, Sedelnikova O, Newrock K, Bonner W. Redon C, et al. Curr Opin Genet Dev. 2002 Apr;12(2):162-9. doi: 10.1016/s0959-437x(02)00282-4. Curr Opin Genet Dev. 2002. PMID: 11893489 Review.
Histone H2AX in DNA damage and repair.
Sedelnikova OA, Pilch DR, Redon C, Bonner WM. Sedelnikova OA, et al. Among authors: bonner wm. Cancer Biol Ther. 2003 May-Jun;2(3):233-5. doi: 10.4161/cbt.2.3.373. Cancer Biol Ther. 2003. PMID: 12878854 Review. No abstract available.
GammaH2AX and cancer.
Bonner WM, Redon CE, Dickey JS, Nakamura AJ, Sedelnikova OA, Solier S, Pommier Y. Bonner WM, et al. Nat Rev Cancer. 2008 Dec;8(12):957-67. doi: 10.1038/nrc2523. Epub 2008 Nov 13. Nat Rev Cancer. 2008. PMID: 19005492 Free PMC article. Review.
H2AX: functional roles and potential applications.
Dickey JS, Redon CE, Nakamura AJ, Baird BJ, Sedelnikova OA, Bonner WM. Dickey JS, et al. Among authors: bonner wm. Chromosoma. 2009 Dec;118(6):683-92. doi: 10.1007/s00412-009-0234-4. Epub 2009 Aug 26. Chromosoma. 2009. PMID: 19707781 Free PMC article. Review.
183 results