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Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay.
Ji J, Zhang Y, Redon CE, Reinhold WC, Chen AP, Fogli LK, Holbeck SL, Parchment RE, Hollingshead M, Tomaszewski JE, Dudon Q, Pommier Y, Doroshow JH, Bonner WM. Ji J, et al. Among authors: holbeck sl. PLoS One. 2017 Feb 3;12(2):e0171582. doi: 10.1371/journal.pone.0171582. eCollection 2017. PLoS One. 2017. PMID: 28158293 Free PMC article.
The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology.
Abaan OD, Polley EC, Davis SR, Zhu YJ, Bilke S, Walker RL, Pineda M, Gindin Y, Jiang Y, Reinhold WC, Holbeck SL, Simon RM, Doroshow JH, Pommier Y, Meltzer PS. Abaan OD, et al. Among authors: holbeck sl. Cancer Res. 2013 Jul 15;73(14):4372-82. doi: 10.1158/0008-5472.CAN-12-3342. Epub 2013 Jul 15. Cancer Res. 2013. PMID: 23856246 Free PMC article.
The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity.
Holbeck SL, Camalier R, Crowell JA, Govindharajulu JP, Hollingshead M, Anderson LW, Polley E, Rubinstein L, Srivastava A, Wilsker D, Collins JM, Doroshow JH. Holbeck SL, et al. Cancer Res. 2017 Jul 1;77(13):3564-3576. doi: 10.1158/0008-5472.CAN-17-0489. Epub 2017 Apr 26. Cancer Res. 2017. PMID: 28446463 Free PMC article.
Bisindenoisoquinoline bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA intercalator and topoisomerase inhibitor with antitumor activity.
Antony S, Agama KK, Miao ZH, Hollingshead M, Holbeck SL, Wright MH, Varticovski L, Nagarajan M, Morrell A, Cushman M, Pommier Y. Antony S, et al. Among authors: holbeck sl. Mol Pharmacol. 2006 Sep;70(3):1109-20. doi: 10.1124/mol.106.024372. Epub 2006 Jun 23. Mol Pharmacol. 2006. PMID: 16798938
Predicting tumor cell line response to drug pairs with deep learning.
Xia F, Shukla M, Brettin T, Garcia-Cardona C, Cohn J, Allen JE, Maslov S, Holbeck SL, Doroshow JH, Evrard YA, Stahlberg EA, Stevens RL. Xia F, et al. Among authors: holbeck sl. BMC Bioinformatics. 2018 Dec 21;19(Suppl 18):486. doi: 10.1186/s12859-018-2509-3. BMC Bioinformatics. 2018. PMID: 30577754 Free PMC article.
46 results