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Page 1
Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations.
Hou TZ, Verma N, Wanders J, Kennedy A, Soskic B, Janman D, Halliday N, Rowshanravan B, Worth A, Qasim W, Baxendale H, Stauss H, Seneviratne S, Neth O, Olbrich P, Hambleton S, Arkwright PD, Burns SO, Walker LS, Sansom DM. Hou TZ, et al. Among authors: rowshanravan b. Blood. 2017 Mar 16;129(11):1458-1468. doi: 10.1182/blood-2016-10-745174. Epub 2017 Feb 3. Blood. 2017. PMID: 28159733 Free PMC article.
CTLA-4: a moving target in immunotherapy.
Rowshanravan B, Halliday N, Sansom DM. Rowshanravan B, et al. Blood. 2018 Jan 4;131(1):58-67. doi: 10.1182/blood-2017-06-741033. Epub 2017 Nov 8. Blood. 2018. PMID: 29118008 Free PMC article. Review.
CD80 on Human T Cells Is Associated With FoxP3 Expression and Supports Treg Homeostasis.
Soskic B, Jeffery LE, Kennedy A, Gardner DH, Hou TZ, Halliday N, Williams C, Janman D, Rowshanravan B, Hirschfield GM, Sansom DM. Soskic B, et al. Among authors: rowshanravan b. Front Immunol. 2021 Jan 8;11:577655. doi: 10.3389/fimmu.2020.577655. eCollection 2020. Front Immunol. 2021. PMID: 33488578 Free PMC article.
Regulation of CTLA-4 recycling by LRBA and Rab11.
Janman D, Hinze C, Kennedy A, Halliday N, Waters E, Williams C, Rowshanravan B, Hou TZ, Minogue S, Qureshi OS, Sansom DM. Janman D, et al. Among authors: rowshanravan b. Immunology. 2021 Sep;164(1):106-119. doi: 10.1111/imm.13343. Epub 2021 Jun 6. Immunology. 2021. PMID: 33960403 Free PMC article.
Characterization of CTLA4 Trafficking and Implications for Its Function.
Khailaie S, Rowshanravan B, Robert PA, Waters E, Halliday N, Badillo Herrera JD, Walker LSK, Sansom DM, Meyer-Hermann M. Khailaie S, et al. Among authors: rowshanravan b. Biophys J. 2018 Oct 2;115(7):1330-1343. doi: 10.1016/j.bpj.2018.08.020. Epub 2018 Aug 23. Biophys J. 2018. PMID: 30219287 Free PMC article.
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation.
Kennedy A, Waters E, Rowshanravan B, Hinze C, Williams C, Janman D, Fox TA, Booth C, Pesenacker AM, Halliday N, Soskic B, Kaur S, Qureshi OS, Morris EC, Ikemizu S, Paluch C, Huo J, Davis SJ, Boucrot E, Walker LSK, Sansom DM. Kennedy A, et al. Among authors: rowshanravan b. Nat Immunol. 2022 Sep;23(9):1365-1378. doi: 10.1038/s41590-022-01289-w. Epub 2022 Aug 23. Nat Immunol. 2022. PMID: 35999394 Free PMC article.