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Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.
Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, Hokanson JE, Crapo JD, Castaldi PJ, Chase RP, Bartz TM, Heckbert SR, Psaty BM, Gharib SA, Zanen P, Lammers JW, Oudkerk M, Groen HJ, Locantore N, Tal-Singer R, Rennard SI, Vestbo J, Timens W, Paré PD, Latourelle JC, Dupuis J, O'Connor GT, Wilk JB, Kim WJ, Lee MK, Oh YM, Vonk JM, de Koning HJ, Leng S, Belinsky SA, Tesfaigzi Y, Manichaikul A, Wang XQ, Rich SS, Barr RG, Sparrow D, Litonjua AA, Bakke P, Gulsvik A, Lahousse L, Brusselle GG, Stricker BH, Uitterlinden AG, Ampleford EJ, Bleecker ER, Woodruff PG, Meyers DA, Qiao D, Lomas DA, Yim JJ, Kim DK, Hawrylkiewicz I, Sliwinski P, Hardin M, Fingerlin TE, Schwartz DA, Postma DS, MacNee W, Tobin MD, Silverman EK, Boezen HM, Cho MH; COPDGene Investigators; ECLIPSE Investigators; LifeLines Investigators; SPIROMICS Research Group; International COPD Genetics Network Investigators; UK BiLEVE Investigators; International COPD Genetics Consortium. Hobbs BD, et al. Among authors: silverman ek. Nat Genet. 2017 Mar;49(3):426-432. doi: 10.1038/ng.3752. Epub 2017 Feb 6. Nat Genet. 2017. PMID: 28166215 Free PMC article.
A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary disease.
Kelleher CM, Silverman EK, Broekelmann T, Litonjua AA, Hernandez M, Sylvia JS, Stoler J, Reilly JJ, Chapman HA, Speizer FE, Weiss ST, Mecham RP, Raby BA. Kelleher CM, et al. Among authors: silverman ek. Am J Respir Cell Mol Biol. 2005 Oct;33(4):355-62. doi: 10.1165/rcmb.2005-0206OC. Epub 2005 Aug 4. Am J Respir Cell Mol Biol. 2005. PMID: 16081882 Free PMC article.
Genetics of chronic obstructive pulmonary disease.
DeMeo DL, Silverman EK. DeMeo DL, et al. Among authors: silverman ek. Semin Respir Crit Care Med. 2003 Apr;24(2):151-60. doi: 10.1055/s-2003-39014. Semin Respir Crit Care Med. 2003. PMID: 16088534
T-bet polymorphisms are associated with asthma and airway hyperresponsiveness.
Raby BA, Hwang ES, Van Steen K, Tantisira K, Peng S, Litonjua A, Lazarus R, Giallourakis C, Rioux JD, Sparrow D, Silverman EK, Glimcher LH, Weiss ST. Raby BA, et al. Among authors: silverman ek. Am J Respir Crit Care Med. 2006 Jan 1;173(1):64-70. doi: 10.1164/rccm.200503-505OC. Epub 2005 Sep 22. Am J Respir Crit Care Med. 2006. PMID: 16179640 Free PMC article.
The SERPINE2 gene is associated with chronic obstructive pulmonary disease.
Demeo DL, Mariani TJ, Lange C, Srisuma S, Litonjua AA, Celedon JC, Lake SL, Reilly JJ, Chapman HA, Mecham BH, Haley KJ, Sylvia JS, Sparrow D, Spira AE, Beane J, Pinto-Plata V, Speizer FE, Shapiro SD, Weiss ST, Silverman EK. Demeo DL, et al. Among authors: silverman ek. Am J Hum Genet. 2006 Feb;78(2):253-64. doi: 10.1086/499828. Epub 2005 Dec 15. Am J Hum Genet. 2006. PMID: 16358219 Free PMC article.
Genetic association analysis of functional impairment in chronic obstructive pulmonary disease.
Hersh CP, Demeo DL, Lazarus R, Celedón JC, Raby BA, Benditt JO, Criner G, Make B, Martinez FJ, Scanlon PD, Sciurba FC, Utz JP, Reilly JJ, Silverman EK. Hersh CP, et al. Among authors: silverman ek. Am J Respir Crit Care Med. 2006 May 1;173(9):977-84. doi: 10.1164/rccm.200509-1452OC. Epub 2006 Feb 2. Am J Respir Crit Care Med. 2006. PMID: 16456143 Free PMC article.
The SERPINE2 gene is associated with chronic obstructive pulmonary disease.
DeMeo D, Mariani T, Lange C, Lake S, Litonjua A, Celedón J, Reilly J, Chapman HA, Sparrow D, Spira A, Beane J, Pinto-Plata V, Speizer FE, Shapiro S, Weiss ST, Silverman EK. DeMeo D, et al. Among authors: silverman ek. Proc Am Thorac Soc. 2006 Aug;3(6):502. doi: 10.1513/pats.200603-070MS. Proc Am Thorac Soc. 2006. PMID: 16921128 Free article. No abstract available.
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