Griffin MJ - Search Results

1

A population pharmacokinetic model of AT9283 in adults and children to predict the maximum tolerated dose in children with leukaemia.

Duong JK, Griffin MJ, Hargrave D, Vormoor J, Edwards D, Boddy AV. Duong JK, et al. Among authors: griffin mj. Br J Clin Pharmacol. 2017 Aug;83(8):1713-1722. doi: 10.1111/bcp.13260. Epub 2017 Mar 5. Br J Clin Pharmacol. 2017. PMID: 28177130 Free PMC article.

2

A phase I trial of AT9283 (a selective inhibitor of aurora kinases) in children and adolescents with solid tumors: a Cancer Research UK study.

Moreno L, Marshall LV, Pearson AD, Morland B, Elliott M, Campbell-Hewson Q, Makin G, Halford SE, Acton G, Ross P, Kazmi-Stokes S, Lock V, Rodriguez A, Lyons JF, Boddy AV, Griffin MJ, Yule M, Hargrave D. Moreno L, et al. Among authors: griffin mj. Clin Cancer Res. 2015 Jan 15;21(2):267-73. doi: 10.1158/1078-0432.CCR-14-1592. Epub 2014 Nov 4. Clin Cancer Res. 2015. PMID: 25370467 Clinical Trial.

3

A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia.

Vormoor B, Veal GJ, Griffin MJ, Boddy AV, Irving J, Minto L, Case M, Banerji U, Swales KE, Tall JR, Moore AS, Toguchi M, Acton G, Dyer K, Schwab C, Harrison CJ, Grainger JD, Lancaster D, Kearns P, Hargrave D, Vormoor J. Vormoor B, et al. Among authors: griffin mj. Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26351. Epub 2016 Dec 1. Pediatr Blood Cancer. 2017. PMID: 27905678 Clinical Trial.

4

A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours.

Plummer R, Wilson RH, Calvert H, Boddy AV, Griffin M, Sludden J, Tilby MJ, Eatock M, Pearson DG, Ottley CJ, Matsumura Y, Kataoka K, Nishiya T. Plummer R, et al. Among authors: griffin m. Br J Cancer. 2011 Feb 15;104(4):593-8. doi: 10.1038/bjc.2011.6. Epub 2011 Feb 1. Br J Cancer. 2011. PMID: 21285987 Free PMC article. Clinical Trial.

5

Phase I clinical and pharmacokinetic study of pemetrexed and carboplatin in patients with malignant pleural mesothelioma.

Hughes A, Calvert P, Azzabi A, Plummer R, Johnson R, Rusthoven J, Griffin M, Fishwick K, Boddy AV, Verrill M, Calvert H. Hughes A, et al. J Clin Oncol. 2002 Aug 15;20(16):3533-44. doi: 10.1200/JCO.2002.10.073. J Clin Oncol. 2002. PMID: 12177114

6

A phase I and pharmacokinetic study of paclitaxel poliglumex (XYOTAX), investigating both 3-weekly and 2-weekly schedules.

Boddy AV, Plummer ER, Todd R, Sludden J, Griffin M, Robson L, Cassidy J, Bissett D, Bernareggi A, Verrill MW, Calvert AH. Boddy AV, et al. Clin Cancer Res. 2005 Nov 1;11(21):7834-40. doi: 10.1158/1078-0432.CCR-05-0803. Clin Cancer Res. 2005. PMID: 16278406 Clinical Trial.

7

A phase I and pharmacokinetic study of ixabepilone in combination with Carboplatin in patients with advanced solid malignancies.

Plummer R, Woll P, Fyfe D, Boddy AV, Griffin M, Hewitt P, Carmichael J, Namouni F, Cohen M, Verrill M. Plummer R, et al. Clin Cancer Res. 2008 Dec 15;14(24):8288-94. doi: 10.1158/1078-0432.CCR-08-0471. Clin Cancer Res. 2008. PMID: 19088046 Clinical Trial.

8

Clinical pharmacokinetic and in vitro combination studies of nolatrexed dihydrochloride (AG337, Thymitaq) and paclitaxel.

Hughes AN, Griffin MJ, Newell DR, Calvert AH, Johnston A, Kerr B, Lee C, Liang B, Boddy AV. Hughes AN, et al. Among authors: griffin mj. Br J Cancer. 2000 May;82(9):1519-27. doi: 10.1054/bjoc.2000.1172. Br J Cancer. 2000. PMID: 10789718 Free PMC article. Clinical Trial.

9

A phase I study in paediatric patients to evaluate the safety and pharmacokinetics of SPI-77, a liposome encapsulated formulation of cisplatin.

Veal GJ, Griffin MJ, Price E, Parry A, Dick GS, Little MA, Yule SM, Morland B, Estlin EJ, Hale JP, Pearson AD, Welbank H, Boddy AV. Veal GJ, et al. Among authors: griffin mj. Br J Cancer. 2001 Apr 20;84(8):1029-35. doi: 10.1054/bjoc.2001.1723. Br J Cancer. 2001. PMID: 11308249 Free PMC article. Clinical Trial.

10

Pharmacological study of paclitaxel duration of infusion combined with GFR-based carboplatin in the treatment of ovarian cancer.

Boddy AV, Griffin MJ, Sludden J, Thomas HD, Fishwick K, Wright JG, Plumner ER, Highley M, Calvert AH. Boddy AV, et al. Among authors: griffin mj. Cancer Chemother Pharmacol. 2001 Jul;48(1):15-21. doi: 10.1007/s002800100295. Cancer Chemother Pharmacol. 2001. PMID: 11488519 Clinical Trial.

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