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115 results

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A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia.
Vormoor B, Veal GJ, Griffin MJ, Boddy AV, Irving J, Minto L, Case M, Banerji U, Swales KE, Tall JR, Moore AS, Toguchi M, Acton G, Dyer K, Schwab C, Harrison CJ, Grainger JD, Lancaster D, Kearns P, Hargrave D, Vormoor J. Vormoor B, et al. Among authors: vormoor j. Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26351. Epub 2016 Dec 1. Pediatr Blood Cancer. 2017. PMID: 27905678 Clinical Trial.
Early phase clinical trials of anticancer agents in children and adolescents - an ITCC perspective.
Moreno L, Pearson ADJ, Paoletti X, Jimenez I, Geoerger B, Kearns PR, Zwaan CM, Doz F, Baruchel A, Vormoor J, Casanova M, Pfister SM, Morland B, Vassal G; Innovative Therapies for Children with Cancer (ITCC) Consortium. Moreno L, et al. Among authors: vormoor j. Nat Rev Clin Oncol. 2017 Aug;14(8):497-507. doi: 10.1038/nrclinonc.2017.59. Epub 2017 May 16. Nat Rev Clin Oncol. 2017. PMID: 28508875 Free article. Review.
The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia.
Eswaran J, Sinclair P, Heidenreich O, Irving J, Russell LJ, Hall A, Calado DP, Harrison CJ, Vormoor J. Eswaran J, et al. Among authors: vormoor j. Leukemia. 2015 Aug;29(8):1623-31. doi: 10.1038/leu.2015.113. Epub 2015 May 6. Leukemia. 2015. PMID: 25943180 Review.
Selumetinib in combination with dexamethasone for the treatment of relapsed/refractory RAS-pathway mutated paediatric and adult acute lymphoblastic leukaemia (SeluDex): study protocol for an international, parallel-group, dose-finding with expansion phase I/II trial.
Menne T, Slade D, Savage J, Johnson S, Irving J, Kearns P, Plummer R, Shenton G, Veal GJ, Vormoor B, Vormoor J, Billingham L. Menne T, et al. Among authors: vormoor j. BMJ Open. 2022 Mar 4;12(3):e059872. doi: 10.1136/bmjopen-2021-059872. BMJ Open. 2022. PMID: 35246426 Free PMC article.
Understanding the cancer stem cell.
Bomken S, Fiser K, Heidenreich O, Vormoor J. Bomken S, et al. Among authors: vormoor j. Br J Cancer. 2010 Aug 10;103(4):439-45. doi: 10.1038/sj.bjc.6605821. Epub 2010 Jul 27. Br J Cancer. 2010. PMID: 20664590 Free PMC article. Review.
Leukaemia & cancer in neonates.
Vormoor J, Chintagumpala M. Vormoor J, et al. Semin Fetal Neonatal Med. 2012 Aug;17(4):183-184. doi: 10.1016/j.siny.2012.04.001. Epub 2012 May 8. Semin Fetal Neonatal Med. 2012. PMID: 22572199 No abstract available.
From class waivers to precision medicine in paediatric oncology.
Pearson ADJ, Pfister SM, Baruchel A, Bourquin JP, Casanova M, Chesler L, Doz F, Eggert A, Geoerger B, Jones DTW, Kearns PR, Molenaar JJ, Morland B, Schleiermacher G, Schulte JH, Vormoor J, Marshall LV, Zwaan CM, Vassal G; Executive and Biology Committees of the Innovative Therapies for Children with Cancer European Consortium. Pearson ADJ, et al. Among authors: vormoor j. Lancet Oncol. 2017 Jul;18(7):e394-e404. doi: 10.1016/S1470-2045(17)30442-4. Lancet Oncol. 2017. PMID: 28677575 Review.
Accelerating drug development in pediatric cancer: a novel Phase I study design of venetoclax in relapsed/refractory malignancies.
Place AE, Goldsmith K, Bourquin JP, Loh ML, Gore L, Morgenstern DA, Sanzgiri Y, Hoffman D, Zhou Y, Ross JA, Prine B, Shebley M, McNamee M, Farazi T, Kim SY, Verdugo M, Lash-Fleming L, Zwaan CM, Vormoor J. Place AE, et al. Among authors: vormoor j. Future Oncol. 2018 Sep;14(21):2115-2129. doi: 10.2217/fon-2018-0121. Epub 2018 Mar 29. Future Oncol. 2018. PMID: 29595064 Free article. Clinical Trial.
115 results