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Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis.
Anal Chem. 2017 Feb 21;89(4):2250-2258. doi: 10.1021/acs.analchem.6b03058. Epub 2017 Feb 9.
Anal Chem. 2017.
PMID: 28193005
Free PMC article.
Engineering of stable bispecific antibodies targeting IL-17A and IL-23.
Mabry R, Lewis KE, Moore M, McKernan PA, Bukowski TR, Bontadelli K, Brender T, Okada S, Lum K, West J, Kuijper JL, Ardourel D, Franke S, Lockwood L, Vu T, Frank A, Appleby MW, Wolf A, Reardon B, Hamacher NB, Stevens B, Lewis P, Lewis KB, Gilbertson DG, Lantry M, Julien SH, Ostrander C, Chan C, Byrnes-Blake K, Brody J, Presnell S, Meengs B, Levin SD, Snavely M.
Mabry R, et al.
Protein Eng Des Sel. 2010 Mar;23(3):115-27. doi: 10.1093/protein/gzp073. Epub 2009 Dec 18.
Protein Eng Des Sel. 2010.
PMID: 20022918
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Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F.
Kuestner RE, Taft DW, Haran A, Brandt CS, Brender T, Lum K, Harder B, Okada S, Ostrander CD, Kreindler JL, Aujla SJ, Reardon B, Moore M, Shea P, Schreckhise R, Bukowski TR, Presnell S, Guerra-Lewis P, Parrish-Novak J, Ellsworth JL, Jaspers S, Lewis KE, Appleby M, Kolls JK, Rixon M, West JW, Gao Z, Levin SD.
Kuestner RE, et al.
J Immunol. 2007 Oct 15;179(8):5462-73. doi: 10.4049/jimmunol.179.8.5462.
J Immunol. 2007.
PMID: 17911633
Free PMC article.
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Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions.
Parrish-Novak J, Xu W, Brender T, Yao L, Jones C, West J, Brandt C, Jelinek L, Madden K, McKernan PA, Foster DC, Jaspers S, Chandrasekher YA.
Parrish-Novak J, et al.
J Biol Chem. 2002 Dec 6;277(49):47517-23. doi: 10.1074/jbc.M205114200. Epub 2002 Sep 25.
J Biol Chem. 2002.
PMID: 12351624
Free article.
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A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist.
Xu W, Presnell SR, Parrish-Novak J, Kindsvogel W, Jaspers S, Chen Z, Dillon SR, Gao Z, Gilbert T, Madden K, Schlutsmeyer S, Yao L, Whitmore TE, Chandrasekher Y, Grant FJ, Maurer M, Jelinek L, Storey H, Brender T, Hammond A, Topouzis S, Clegg CH, Foster DC.
Xu W, et al.
Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9511-6. doi: 10.1073/pnas.171303198. Epub 2001 Jul 31.
Proc Natl Acad Sci U S A. 2001.
PMID: 11481447
Free PMC article.
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Interleukin 20: discovery, receptor identification, and role in epidermal function.
Blumberg H, Conklin D, Xu WF, Grossmann A, Brender T, Carollo S, Eagan M, Foster D, Haldeman BA, Hammond A, Haugen H, Jelinek L, Kelly JD, Madden K, Maurer MF, Parrish-Novak J, Prunkard D, Sexson S, Sprecher C, Waggie K, West J, Whitmore TE, Yao L, Kuechle MK, Dale BA, Chandrasekher YA.
Blumberg H, et al.
Cell. 2001 Jan 12;104(1):9-19. doi: 10.1016/s0092-8674(01)00187-8.
Cell. 2001.
PMID: 11163236
Free article.
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Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes.
Hippen KL, Bucher C, Schirm DK, Bearl AM, Brender T, Mink KA, Waggie KS, Peffault de Latour R, Janin A, Curtsinger JM, Dillon SR, Miller JS, Socie G, Blazar BR.
Hippen KL, et al.
Blood. 2012 Jan 12;119(2):619-28. doi: 10.1182/blood-2011-07-368027. Epub 2011 Nov 10.
Blood. 2012.
PMID: 22077059
Free PMC article.
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PD-1 blockade enhances elotuzumab efficacy in mouse tumor models.
Bezman NA, Jhatakia A, Kearney AY, Brender T, Maurer M, Henning K, Jenkins MR, Rogers AJ, Neeson PJ, Korman AJ, Robbins MD, Graziano RF.
Bezman NA, et al.
Blood Adv. 2017 May 8;1(12):753-765. doi: 10.1182/bloodadvances.2017004382. eCollection 2017 May 9.
Blood Adv. 2017.
PMID: 29296719
Free PMC article.
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