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Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer.
Delaney JR, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, Tancioni I, Lu D, Bapat J, Young S, Cadassou O, Bartakova A, Sheth P, Haft C, Hui S, Saenz C, Schlaepfer DD, Harismendy O, Stupack DG. Delaney JR, et al. Among authors: bapat j. Nat Commun. 2017 Feb 15;8:14423. doi: 10.1038/ncomms14423. Nat Commun. 2017. PMID: 28198375 Free PMC article.
Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors.
Delaney JR, Patel CB, Bapat J, Jones CM, Ramos-Zapatero M, Ortell KK, Tanios R, Haghighiabyaneh M, Axelrod J, DeStefano JW, Tancioni I, Schlaepfer DD, Harismendy O, La Spada AR, Stupack DG. Delaney JR, et al. Among authors: bapat j. PLoS Genet. 2020 Jan 10;16(1):e1008558. doi: 10.1371/journal.pgen.1008558. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31923184 Free PMC article.
ATF6-Mediated Signaling Contributes to PARP Inhibitor Resistance in Ovarian Cancer.
McMellen A, Yamamoto TM, Qamar L, Sanders BE, Nguyen LL, Ortiz Chavez D, Bapat J, Berning A, Post MD, Johnson J, Behbakht K, Nurmemmedov E, Chuong EB, Bitler BG. McMellen A, et al. Among authors: bapat j. Mol Cancer Res. 2023 Jan 3;21(1):3-13. doi: 10.1158/1541-7786.MCR-22-0102. Mol Cancer Res. 2023. PMID: 36149636 Free PMC article.
Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions.
Aguilar-Calvo P, Sevillano AM, Bapat J, Soldau K, Sandoval DR, Altmeppen HC, Linsenmeier L, Pizzo DP, Geschwind MD, Sanchez H, Appleby BS, Cohen ML, Safar JG, Edland SD, Glatzel M, Nilsson KPR, Esko JD, Sigurdson CJ. Aguilar-Calvo P, et al. Among authors: bapat j. Acta Neuropathol. 2020 Mar;139(3):527-546. doi: 10.1007/s00401-019-02085-x. Epub 2019 Oct 31. Acta Neuropathol. 2020. PMID: 31673874 Free PMC article.
Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection.
Aguilar-Calvo P, Malik A, Sandoval DR, Barback C, Orrù CD, Standke HG, Thomas OR, Dwyer CA, Pizzo DP, Bapat J, Soldau K, Ogawa R, Riley MB, Nilsson KPR, Kraus A, Caughey B, Iliff JJ, Vera DR, Esko JD, Sigurdson CJ. Aguilar-Calvo P, et al. Among authors: bapat j. PLoS Pathog. 2023 Sep 25;19(9):e1011487. doi: 10.1371/journal.ppat.1011487. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37747931 Free PMC article.
39 results