Fleishman SJ - Search Results

1

Collective repacking reveals that the structures of protein cores are uniquely specified by steric repulsive interactions.

Gaines JC, Virrueta A, Buch DA, Fleishman SJ, O'Hern CS, Regan L. Gaines JC, et al. Among authors: fleishman sj. Protein Eng Des Sel. 2017 May 1;30(5):387-394. doi: 10.1093/protein/gzx011. Protein Eng Des Sel. 2017. PMID: 28201818 Free PMC article.

2

Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.

Grossman I, Ilani T, Fleishman SJ, Fass D. Grossman I, et al. Among authors: fleishman sj. Protein Eng Des Sel. 2016 Apr;29(4):135-47. doi: 10.1093/protein/gzv067. Epub 2016 Jan 26. Protein Eng Des Sel. 2016. PMID: 26819240 Free PMC article.

3

Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers.

Goldsmith M, Aggarwal N, Ashani Y, Jubran H, Greisen PJ, Ovchinnikov S, Leader H, Baker D, Sussman JL, Goldenzweig A, Fleishman SJ, Tawfik DS. Goldsmith M, et al. Among authors: fleishman sj. Protein Eng Des Sel. 2017 Apr 1;30(4):333-345. doi: 10.1093/protein/gzx003. Protein Eng Des Sel. 2017. PMID: 28159998

4

A lipophilicity-based energy function for membrane-protein modelling and design.

Weinstein JY, Elazar A, Fleishman SJ. Weinstein JY, et al. Among authors: fleishman sj. PLoS Comput Biol. 2019 Aug 28;15(8):e1007318. doi: 10.1371/journal.pcbi.1007318. eCollection 2019 Aug. PLoS Comput Biol. 2019. PMID: 31461441 Free PMC article.

5

Stabilization of the SARS-CoV-2 receptor binding domain by protein core redesign and deep mutational scanning.

Leonard AC, Weinstein JJ, Steiner PJ, Erbse AH, Fleishman SJ, Whitehead TA. Leonard AC, et al. Among authors: fleishman sj. Protein Eng Des Sel. 2022 Feb 17;35:gzac002. doi: 10.1093/protein/gzac002. Protein Eng Des Sel. 2022. PMID: 35325236 Free PMC article.

6

Rosetta in CAPRI rounds 13-19.

Fleishman SJ, Corn JE, Strauch EM, Whitehead TA, Andre I, Thompson J, Havranek JJ, Das R, Bradley P, Baker D. Fleishman SJ, et al. Proteins. 2010 Nov 15;78(15):3212-8. doi: 10.1002/prot.22784. Proteins. 2010. PMID: 20597089 Free PMC article.

7

Restricted sidechain plasticity in the structures of native proteins and complexes.

Fleishman SJ, Khare SD, Koga N, Baker D. Fleishman SJ, et al. Protein Sci. 2011 Apr;20(4):753-7. doi: 10.1002/pro.604. Protein Sci. 2011. PMID: 21432939 Free PMC article.

8

Role of the biomolecular energy gap in protein design, structure, and evolution.

Fleishman SJ, Baker D. Fleishman SJ, et al. Cell. 2012 Apr 13;149(2):262-73. doi: 10.1016/j.cell.2012.03.016. Cell. 2012. PMID: 22500796 Free article.

9

Computational design of protein-protein interactions.

Schreiber G, Fleishman SJ. Schreiber G, et al. Among authors: fleishman sj. Curr Opin Struct Biol. 2013 Dec;23(6):903-10. doi: 10.1016/j.sbi.2013.08.003. Epub 2013 Aug 29. Curr Opin Struct Biol. 2013. PMID: 23993666 Review.

10

Why reinvent the wheel? Building new proteins based on ready-made parts.

Khersonsky O, Fleishman SJ. Khersonsky O, et al. Among authors: fleishman sj. Protein Sci. 2016 Jul;25(7):1179-87. doi: 10.1002/pro.2892. Epub 2016 Feb 22. Protein Sci. 2016. PMID: 26821641 Free PMC article. Review.

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