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Page 1
A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus.
Kumar D, Puan KJ, Andiappan AK, Lee B, Westerlaken GH, Haase D, Melchiotti R, Li Z, Yusof N, Lum J, Koh G, Foo S, Yeong J, Alves AC, Pekkanen J, Sun LD, Irwanto A, Fairfax BP, Naranbhai V, Common JE, Tang M, Chuang CK, Jarvelin MR, Knight JC, Zhang X, Chew FT, Prabhakar S, Jianjun L, Wang Y, Zolezzi F, Poidinger M, Lane EB, Meyaard L, Rötzschke O. Kumar D, et al. Among authors: irwanto a. Genome Med. 2017 Feb 20;9(1):18. doi: 10.1186/s13073-017-0404-6. Genome Med. 2017. PMID: 28219444 Free PMC article.
Genome-wide analysis of the genetic regulation of gene expression in human neutrophils.
Andiappan AK, Melchiotti R, Poh TY, Nah M, Puan KJ, Vigano E, Haase D, Yusof N, San Luis B, Lum J, Kumar D, Foo S, Zhuang L, Vasudev A, Irwanto A, Lee B, Nardin A, Liu H, Zhang F, Connolly J, Liu J, Mortellaro A, Wang Y, Poidinger M, Larbi A, Zolezzi F, Rotzschke O. Andiappan AK, et al. Among authors: irwanto a. Nat Commun. 2015 Aug 10;6:7971. doi: 10.1038/ncomms8971. Nat Commun. 2015. PMID: 26259071 Free PMC article.
A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis.
Jin P, Andiappan AK, Quek JM, Lee B, Au B, Sio YY, Irwanto A, Schurmann C, Grabe HJ, Suri BK, Matta SA, Westra HJ, Franke L, Esko T, Sun L, Zhang X, Liu H, Zhang F, Larbi A, Xu X, Poidinger M, Liu J, Chew FT, Rotzschke O, Shi L, Wang de Y. Jin P, et al. Among authors: irwanto a. J Allergy Clin Immunol. 2015 Jun;135(6):1486-93.e8. doi: 10.1016/j.jaci.2014.12.1870. Epub 2015 Jan 30. J Allergy Clin Immunol. 2015. PMID: 25649076
Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.
Liu H, Irwanto A, Fu X, Yu G, Yu Y, Sun Y, Wang C, Wang Z, Okada Y, Low H, Li Y, Liany H, Chen M, Bao F, Li J, You J, Zhang Q, Liu J, Chu T, Andiappan AK, Wang N, Niu G, Liu D, Yu X, Zhang L, Tian H, Zhou G, Rotzschke O, Chen S, Zhang X, Liu J, Zhang F. Liu H, et al. Among authors: irwanto a. Nat Genet. 2015 Mar;47(3):267-71. doi: 10.1038/ng.3212. Epub 2015 Feb 2. Nat Genet. 2015. PMID: 25642632
Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.
Sun Y, Irwanto A, Toyo-Oka L, Hong M, Liu H, Andiappan AK, Choi H, Hitomi Y, Yu G, Yu Y, Bao F, Wang C, Fu X, Yue Z, Wang H, Zhang H, Kawashima M, Kojima K, Nagasaki M, Nakamura M, Yang SK, Ye BD, Denise Y, Rotzschke O, Song K, Tokunaga K, Zhang F, Liu J. Sun Y, et al. Among authors: irwanto a. Sci Rep. 2016 Aug 10;6:31429. doi: 10.1038/srep31429. Sci Rep. 2016. PMID: 27507062 Free PMC article.
Genome-Wide Analysis of Protein-Coding Variants in Leprosy.
Liu H, Wang Z, Li Y, Yu G, Fu X, Wang C, Liu W, Yu Y, Bao F, Irwanto A, Liu J, Chu T, Andiappan AK, Maurer-Stroh S, Limviphuvadh V, Wang H, Mi Z, Sun Y, Sun L, Wang L, Wang C, You J, Li J, Foo JN, Liany H, Meah WY, Niu G, Yue Z, Zhao Q, Wang N, Yu M, Yu W, Cheng X, Khor CC, Sim KS, Aung T, Wang N, Wang D, Shi L, Ning Y, Zheng Z, Yang R, Li J, Yang J, Yan L, Shen J, Zhang G, Chen S, Liu J, Zhang F. Liu H, et al. Among authors: irwanto a. J Invest Dermatol. 2017 Dec;137(12):2544-2551. doi: 10.1016/j.jid.2017.08.004. Epub 2017 Aug 24. J Invest Dermatol. 2017. PMID: 28842327 Free article.
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.
Siddiq A, Couch FJ, Chen GK, Lindström S, Eccles D, Millikan RC, Michailidou K, Stram DO, Beckmann L, Rhie SK, Ambrosone CB, Aittomäki K, Amiano P, Apicella C; Australian Breast Cancer Tissue Bank Investigators; Baglietto L, Bandera EV, Beckmann MW, Berg CD, Bernstein L, Blomqvist C, Brauch H, Brinton L, Bui QM, Buring JE, Buys SS, Campa D, Carpenter JE, Chasman DI, Chang-Claude J, Chen C, Clavel-Chapelon F, Cox A, Cross SS, Czene K, Deming SL, Diasio RB, Diver WR, Dunning AM, Durcan L, Ekici AB, Fasching PA; Familial Breast Cancer Study; Feigelson HS, Fejerman L, Figueroa JD, Fletcher O, Flesch-Janys D, Gaudet MM; GENICA Consortium; Gerty SM, Rodriguez-Gil JL, Giles GG, van Gils CH, Godwin AK, Graham N, Greco D, Hall P, Hankinson SE, Hartmann A, Hein R, Heinz J, Hoover RN, Hopper JL, Hu JJ, Huntsman S, Ingles SA, Irwanto A, Isaacs C, Jacobs KB, John EM, Justenhoven C, Kaaks R, Kolonel LN, Coetzee GA, Lathrop M, Le Marchand L, Lee AM, Lee IM, Lesnick T, Lichtner P, Liu J, Lund E, Makalic E, Martin NG, McLean CA, Meijers-Heijboer H, Meindl A, Miron P, Monroe KR, Montgomery GW, Müller-Myhsok B, Nickels S, Nyante SJ, Olswold C, Overvad K, Palli D, Park DJ, Palmer JR, Pathak H,… See abstract for full author list ➔ Siddiq A, et al. Among authors: irwanto a. Hum Mol Genet. 2012 Dec 15;21(24):5373-84. doi: 10.1093/hmg/dds381. Epub 2012 Sep 13. Hum Mol Genet. 2012. PMID: 22976474 Free PMC article.
An association study of TOLL and CARD with leprosy susceptibility in Chinese population.
Liu H, Bao F, Irwanto A, Fu X, Lu N, Yu G, Yu Y, Sun Y, Low H, Li Y, Liany H, Yuan C, Li J, Liu J, Chen M, Liu H, Wang N, You J, Ma S, Niu G, Zhou Y, Chu T, Tian H, Chen S, Zhang X, Liu J, Zhang F. Liu H, et al. Among authors: irwanto a. Hum Mol Genet. 2013 Nov 1;22(21):4430-7. doi: 10.1093/hmg/ddt286. Epub 2013 Jun 19. Hum Mol Genet. 2013. PMID: 23784377 Free PMC article.
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N; Breast and Ovarian Cancer Susceptibility Collaboration; Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K, Irwanto A, Liu J, Waisfisz Q, Meijers-Heijboer H, Adank M; Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON); van der Luijt RB, Hein R, Dahmen N, Beckman L, Meindl A, Schmutzler RK, Müller-Myhsok B, Lichtner P, Hopper JL, Southey MC, Makalic E, Schmidt DF, Uitterlinden AG, Hofman A, Hunter DJ, Chanock SJ, Vincent D, Bacot F, Tessier DC, Canisius S, Wessels LF, Haiman CA, Shah M, Luben R, Brown J, Luccarini C, Schoof N, Humphreys K, Li J, Nordestgaard BG, Nielsen SF, Flyger H, Couch FJ, Wang X, Vachon C, Stevens KN, Lambrechts D, Moisse M, Paridaens R, Christiaens MR, Rudolph A, Nickels S, Flesch-Janys D, Johnson N, Aitken Z, Aaltonen K, Heikkinen T, Broeks A, Veer LJ, van der Schoot CE, Guénel P, Truong T, Laurent-Puig P, Menegaux F, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Zamora MP, Perez JI, Pita G, Alonso MR, Cox… See abstract for full author list ➔ Michailidou K, et al. Among authors: irwanto a. Nat Genet. 2013 Apr;45(4):353-61, 361e1-2. doi: 10.1038/ng.2563. Nat Genet. 2013. PMID: 23535729 Free PMC article.
Identification of IL18RAP/IL18R1 and IL12B as leprosy risk genes demonstrates shared pathogenesis between inflammation and infectious diseases.
Liu H, Irwanto A, Tian H, Fu X, Yu Y, Yu G, Low H, Chu T, Li Y, Shi B, Chen M, Sun Y, Yuan C, Lu N, You J, Bao F, Li J, Liu J, Liu H, Liu D, Yu X, Zhang L, Yang Q, Wang N, Niu G, Ma S, Zhou Y, Wang C, Chen S, Zhang X, Liu J, Zhang F. Liu H, et al. Among authors: irwanto a. Am J Hum Genet. 2012 Nov 2;91(5):935-41. doi: 10.1016/j.ajhg.2012.09.010. Epub 2012 Oct 25. Am J Hum Genet. 2012. PMID: 23103228 Free PMC article.
43 results