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Metabolic origins of spatial organization in the tumor microenvironment.
Carmona-Fontaine C, Deforet M, Akkari L, Thompson CB, Joyce JA, Xavier JB. Carmona-Fontaine C, et al. Among authors: akkari l. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2934-2939. doi: 10.1073/pnas.1700600114. Epub 2017 Feb 28. Proc Natl Acad Sci U S A. 2017. PMID: 28246332 Free PMC article.
Single-cell spatial immune landscapes of primary and metastatic brain tumours.
Karimi E, Yu MW, Maritan SM, Perus LJM, Rezanejad M, Sorin M, Dankner M, Fallah P, Doré S, Zuo D, Fiset B, Kloosterman DJ, Ramsay L, Wei Y, Lam S, Alsajjan R, Watson IR, Roldan Urgoiti G, Park M, Brandsma D, Senger DL, Chan JA, Akkari L, Petrecca K, Guiot MC, Siegel PM, Quail DF, Walsh LA. Karimi E, et al. Among authors: akkari l. Nature. 2023 Feb;614(7948):555-563. doi: 10.1038/s41586-022-05680-3. Epub 2023 Feb 1. Nature. 2023. PMID: 36725935 Free PMC article.
Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma.
Mulero-Sánchez A, Ramirez CFA, du Chatinier A, Wang H, Koomen SJI, Song JY, de Groot MHP, Lieftink C, Bosma A, Burylo A, van Tellingen O, Beijersbergen RL, Wang C, Akkari L, Bernards R, Mainardi S. Mulero-Sánchez A, et al. Among authors: akkari l. Mol Oncol. 2023 Jun;17(6):964-980. doi: 10.1002/1878-0261.13377. Epub 2023 Feb 9. Mol Oncol. 2023. PMID: 36650715 Free PMC article.
Non-cell-autonomous tumor suppression by p53.
Lujambio A, Akkari L, Simon J, Grace D, Tschaharganeh DF, Bolden JE, Zhao Z, Thapar V, Joyce JA, Krizhanovsky V, Lowe SW. Lujambio A, et al. Among authors: akkari l. Cell. 2013 Apr 11;153(2):449-60. doi: 10.1016/j.cell.2013.03.020. Epub 2013 Apr 4. Cell. 2013. PMID: 23562644 Free PMC article.
CSF-1R inhibition alters macrophage polarization and blocks glioma progression.
Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie CS, Oei Y, Pedraza A, Zhang J, Brennan CW, Sutton JC, Holland EC, Daniel D, Joyce JA. Pyonteck SM, et al. Among authors: akkari l. Nat Med. 2013 Oct;19(10):1264-72. doi: 10.1038/nm.3337. Epub 2013 Sep 22. Nat Med. 2013. PMID: 24056773 Free PMC article.
mTOR regulates phagosome and entotic vacuole fission.
Krajcovic M, Krishna S, Akkari L, Joyce JA, Overholtzer M. Krajcovic M, et al. Among authors: akkari l. Mol Biol Cell. 2013 Dec;24(23):3736-45. doi: 10.1091/mbc.E13-07-0408. Epub 2013 Oct 2. Mol Biol Cell. 2013. PMID: 24088573 Free PMC article.
48 results