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Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis.
Hellerud BC, Orrem HL, Dybwik K, Pischke SE, Baratt-Due A, Castellheim A, Fure H, Bergseth G, Christiansen D, Nunn MA, Espevik T, Lau C, Brandtzæg P, Nielsen EW, Mollnes TE. Hellerud BC, et al. Among authors: brandtzaeg p. J Intensive Care. 2017 Feb 27;5:21. doi: 10.1186/s40560-017-0217-0. eCollection 2017. J Intensive Care. 2017. PMID: 28261486 Free PMC article.
A new dynamic porcine model of meningococcal shock.
Nielsen EW, Hellerud BC, Thorgersen EB, Castellheim A, Pharo A, Lindstad J, Tønnessen TI, Brandtzaeg P, Mollnes TE. Nielsen EW, et al. Among authors: brandtzaeg p. Shock. 2009 Sep;32(3):302-9. doi: 10.1097/SHK.0b013e31819c37be. Shock. 2009. PMID: 19174740
Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood.
Brekke OL, Hellerud BC, Christiansen D, Fure H, Castellheim A, Nielsen EW, Pharo A, Lindstad JK, Bergseth G, Leslie G, Lambris JD, Brandtzaeg P, Mollnes TE. Brekke OL, et al. Among authors: brandtzaeg p. Mol Immunol. 2011 Sep;48(15-16):2159-69. doi: 10.1016/j.molimm.2011.07.011. Epub 2011 Aug 11. Mol Immunol. 2011. PMID: 21839519 Free PMC article.
Critical roles of complement and antibodies in host defense mechanisms against Neisseria meningitidis as revealed by human complement genetic deficiencies.
Hellerud BC, Aase A, Herstad TK, Naess LM, Kristiansen LH, Trøseid AM, Harboe M, Lappegård KT, Brandtzaeg P, Høiby EA, Mollnes TE. Hellerud BC, et al. Among authors: brandtzaeg p. Infect Immun. 2010 Feb;78(2):802-9. doi: 10.1128/IAI.01044-09. Epub 2009 Nov 23. Infect Immun. 2010. PMID: 19933829 Free PMC article.
Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis.
Brusletto BS, Løberg EM, Hellerud BC, Goverud IL, Berg JP, Olstad OK, Gopinathan U, Brandtzaeg P, Øvstebø R. Brusletto BS, et al. Among authors: brandtzaeg p. Front Cell Infect Microbiol. 2020 Feb 19;10:42. doi: 10.3389/fcimb.2020.00042. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32154187 Free PMC article.
682 results