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SLC22A3 polymorphisms do not modify pancreatic cancer risk, but may influence overall patient survival.
Mohelnikova-Duchonova B, Strouhal O, Hughes DJ, Holcatova I, Oliverius M, Kala Z, Campa D, Rizzato C, Canzian F, Pezzilli R, Talar-Wojnarowska R, Malecka-Panas E, Sperti C, Federico Zambon C, Pedrazzoli S, Fogar P, Milanetto AC, Capurso G, Delle Fave G, Valente R, Gazouli M, Malleo G, Teresa Lawlor R, Strobel O, Hackert T, Giese N, Vodicka P, Vodickova L, Landi S, Tavano F, Gioffreda D, Piepoli A, Pazienza V, Mambrini A, Pedata M, Cantore M, Bambi F, Ermini S, Funel N, Lemstrova R, Soucek P. Mohelnikova-Duchonova B, et al. Among authors: hughes dj. Sci Rep. 2017 Mar 8;7:43812. doi: 10.1038/srep43812. Sci Rep. 2017. PMID: 28272475 Free PMC article.
Genetic variants in selenoprotein genes increase risk of colorectal cancer.
Méplan C, Hughes DJ, Pardini B, Naccarati A, Soucek P, Vodickova L, Hlavatá I, Vrána D, Vodicka P, Hesketh JE. Méplan C, et al. Among authors: hughes dj. Carcinogenesis. 2010 Jun;31(6):1074-9. doi: 10.1093/carcin/bgq076. Epub 2010 Apr 8. Carcinogenesis. 2010. PMID: 20378690
Ornithine decarboxylase G316A genotype and colorectal cancer risk.
Hughes DJ, Hlavatá I, Soucek P, Pardini B, Naccarati A, Vodickova L, O'Morain C, Vodicka P. Hughes DJ, et al. Colorectal Dis. 2011 Aug;13(8):860-4. doi: 10.1111/j.1463-1318.2010.02300.x. Epub 2010 Apr 29. Colorectal Dis. 2011. PMID: 20456464
Hedgehog pathway overexpression in pancreatic cancer is abrogated by new-generation taxoid SB-T-1216.
Mohelnikova-Duchonova B, Kocik M, Duchonova B, Brynychova V, Oliverius M, Hlavsa J, Honsova E, Mazanec J, Kala Z, Ojima I, Hughes DJ, Doherty JE, Murray HA, Crockard MA, Lemstrova R, Soucek P. Mohelnikova-Duchonova B, et al. Among authors: hughes dj. Pharmacogenomics J. 2017 Oct;17(5):452-460. doi: 10.1038/tpj.2016.55. Epub 2016 Aug 30. Pharmacogenomics J. 2017. PMID: 27573236
Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome.
Lemstrova R, Brynychova V, Hughes DJ, Hlavac V, Dvorak P, Doherty JE, Murray HA, Crockard M, Oliverius M, Hlavsa J, Honsova E, Mazanec J, Kala Z, Lovecek M, Havlik R, Ehrmann J, Strouhal O, Soucek P, Melichar B, Mohelnikova-Duchonova B. Lemstrova R, et al. Among authors: hughes dj. Oncol Lett. 2017 Nov;14(5):5980-5988. doi: 10.3892/ol.2017.6946. Epub 2017 Sep 14. Oncol Lett. 2017. PMID: 29113235 Free PMC article.
Functional Polymorphisms in DNA Repair Genes Are Associated with Sporadic Colorectal Cancer Susceptibility and Clinical Outcome.
Jiraskova K, Hughes DJ, Brezina S, Gumpenberger T, Veskrnova V, Buchler T, Schneiderova M, Levy M, Liska V, Vodenkova S, Di Gaetano C, Naccarati A, Pardini B, Vymetalkova V, Gsur A, Vodicka P. Jiraskova K, et al. Among authors: hughes dj. Int J Mol Sci. 2018 Dec 27;20(1):97. doi: 10.3390/ijms20010097. Int J Mol Sci. 2018. PMID: 30591675 Free PMC article.
196 results