Ketchem RR - Search Results

1

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma.

Smith D, Helgason H, Sulem P, Bjornsdottir US, Lim AC, Sveinbjornsson G, Hasegawa H, Brown M, Ketchem RR, Gavala M, Garrett L, Jonasdottir A, Jonasdottir A, Sigurdsson A, Magnusson OT, Eyjolfsson GI, Olafsson I, Onundarson PT, Sigurdardottir O, Gislason D, Gislason T, Ludviksson BR, Ludviksdottir D, Boezen HM, Heinzmann A, Krueger M, Porsbjerg C, Ahluwalia TS, Waage J, Backer V, Deichmann KA, Koppelman GH, Bønnelykke K, Bisgaard H, Masson G, Thorsteinsdottir U, Gudbjartsson DF, Johnston JA, Jonsdottir I, Stefansson K. Smith D, et al. Among authors: ketchem rr. PLoS Genet. 2017 Mar 8;13(3):e1006659. doi: 10.1371/journal.pgen.1006659. eCollection 2017 Mar. PLoS Genet. 2017. PMID: 28273074 Free PMC article.

2

Intermolecular interactions involving an acidic patch on immunoglobulin variable domain and the γ2 constant region mediate crystalline inclusion body formation in the endoplasmic reticulum.

Hasegawa H, Geng M, Ketchem RR, Liu L, Graham K, Jacobsen F. Hasegawa H, et al. Among authors: ketchem rr. Cell Logist. 2017 Aug 8;7(3):e1361499. doi: 10.1080/21592799.2017.1361499. eCollection 2017. Cell Logist. 2017. PMID: 28944095 Free PMC article.

3

A diversity of antibody epitopes can induce signaling through the erythropoietin receptor.

Lim AC, Ketchem RR, Borges L, Carabeo T, Carter J, Hoover JE, Hu Z, Wittekind M, Zhou H, Mehlin C. Lim AC, et al. Among authors: ketchem rr. Biochemistry. 2010 May 11;49(18):3797-804. doi: 10.1021/bi1001147. Biochemistry. 2010. PMID: 20337434

4

Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31.

Shen M, Siu S, Byrd S, Edelmann KH, Patel N, Ketchem RR, Mehlin C, Arnett HA, Hasegawa H. Shen M, et al. Among authors: ketchem rr. Exp Cell Res. 2011 Apr 15;317(7):976-93. doi: 10.1016/j.yexcr.2010.12.012. Epub 2010 Dec 21. Exp Cell Res. 2011. PMID: 21182835

5

A single amino acid difference between human and monkey interleukin (IL)-1beta dictates effective binding to soluble type II IL-1 receptor.

Smith DE, Ketchem RR, Moore H, Anderson Z, Renshaw BR, Friend DJ, Sims JE. Smith DE, et al. Among authors: ketchem rr. J Biol Chem. 2002 Dec 6;277(49):47619-25. doi: 10.1074/jbc.M206636200. Epub 2002 Sep 28. J Biol Chem. 2002. PMID: 12356774 Free article.

6

In vivo crystallization of human IgG in the endoplasmic reticulum of engineered Chinese hamster ovary (CHO) cells.

Hasegawa H, Wendling J, He F, Trilisky E, Stevenson R, Franey H, Kinderman F, Li G, Piedmonte DM, Osslund T, Shen M, Ketchem RR. Hasegawa H, et al. Among authors: ketchem rr. J Biol Chem. 2011 Jun 3;286(22):19917-31. doi: 10.1074/jbc.M110.204362. Epub 2011 Apr 4. J Biol Chem. 2011. PMID: 21464137 Free PMC article.

7

Remediating agitation-induced antibody aggregation by eradicating exposed hydrophobic motifs.

Clark RH, Latypov RF, De Imus C, Carter J, Wilson Z, Manchulenko K, Brown ME, Ketchem RR. Clark RH, et al. Among authors: ketchem rr. MAbs. 2014;6(6):1540-50. doi: 10.4161/mabs.36252. MAbs. 2014. PMID: 25484048 Free PMC article.

8

A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1.

Smith DE, Lipsky BP, Russell C, Ketchem RR, Kirchner J, Hensley K, Huang Y, Friedman WJ, Boissonneault V, Plante MM, Rivest S, Sims JE. Smith DE, et al. Among authors: ketchem rr. Immunity. 2009 Jun 19;30(6):817-31. doi: 10.1016/j.immuni.2009.03.020. Epub 2009 May 28. Immunity. 2009. PMID: 19481478 Free PMC article.

9

Disulfide connectivity of human immunoglobulin G2 structural isoforms.

Martinez T, Guo A, Allen MJ, Han M, Pace D, Jones J, Gillespie R, Ketchem RR, Zhang Y, Balland A. Martinez T, et al. Among authors: ketchem rr. Biochemistry. 2008 Jul 15;47(28):7496-508. doi: 10.1021/bi800576c. Epub 2008 Jun 13. Biochemistry. 2008. PMID: 18549248

10

Four new members expand the interleukin-1 superfamily.

Smith DE, Renshaw BR, Ketchem RR, Kubin M, Garka KE, Sims JE. Smith DE, et al. Among authors: ketchem rr. J Biol Chem. 2000 Jan 14;275(2):1169-75. doi: 10.1074/jbc.275.2.1169. J Biol Chem. 2000. PMID: 10625660 Free article.

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