Lim AC - Search Results

1

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma.

Smith D, Helgason H, Sulem P, Bjornsdottir US, Lim AC, Sveinbjornsson G, Hasegawa H, Brown M, Ketchem RR, Gavala M, Garrett L, Jonasdottir A, Jonasdottir A, Sigurdsson A, Magnusson OT, Eyjolfsson GI, Olafsson I, Onundarson PT, Sigurdardottir O, Gislason D, Gislason T, Ludviksson BR, Ludviksdottir D, Boezen HM, Heinzmann A, Krueger M, Porsbjerg C, Ahluwalia TS, Waage J, Backer V, Deichmann KA, Koppelman GH, Bønnelykke K, Bisgaard H, Masson G, Thorsteinsdottir U, Gudbjartsson DF, Johnston JA, Jonsdottir I, Stefansson K. Smith D, et al. Among authors: lim ac. PLoS Genet. 2017 Mar 8;13(3):e1006659. doi: 10.1371/journal.pgen.1006659. eCollection 2017 Mar. PLoS Genet. 2017. PMID: 28273074 Free PMC article.

2

A diversity of antibody epitopes can induce signaling through the erythropoietin receptor.

Lim AC, Ketchem RR, Borges L, Carabeo T, Carter J, Hoover JE, Hu Z, Wittekind M, Zhou H, Mehlin C. Lim AC, et al. Biochemistry. 2010 May 11;49(18):3797-804. doi: 10.1021/bi1001147. Biochemistry. 2010. PMID: 20337434

3

Russell body phenotype is preferentially induced by IgG mAb clones with high intrinsic condensation propensity: relations between the biosynthetic events in the ER and solution behaviors in vitro.

Hasegawa H, Woods CE, Kinderman F, He F, Lim AC. Hasegawa H, et al. Among authors: lim ac. MAbs. 2014;6(6):1518-32. doi: 10.4161/mabs.36242. MAbs. 2014. PMID: 25484054 Free PMC article.

4

Overexpression of cryoglobulin-like single-chain antibody induces morular cell phenotype via liquid-liquid phase separation in the secretory pathway organelles.

Hasegawa H, Patel N, Lim AC. Hasegawa H, et al. Among authors: lim ac. FEBS J. 2015 Aug;282(15):2777-95. doi: 10.1111/febs.13332. Epub 2015 Jun 19. FEBS J. 2015. PMID: 26036200 Free article.

5

Topogenesis and cell surface trafficking of GPR34 are facilitated by positive-inside rule that effects through a tri-basic motif in the first intracellular loop.

Hasegawa H, Patel N, Ettehadieh E, Li P, Lim AC. Hasegawa H, et al. Among authors: lim ac. Biochim Biophys Acta. 2016 Jul;1863(7 Pt A):1534-51. doi: 10.1016/j.bbamcr.2016.04.010. Epub 2016 Apr 14. Biochim Biophys Acta. 2016. PMID: 27086875 Free article.

6

Modulation of in vivo IgG crystallization in the secretory pathway by heavy chain isotype class switching and N-linked glycosylation.

Hasegawa H, Forte C, Barber I, Turnbaugh S, Stoops J, Shen M, Lim AC. Hasegawa H, et al. Among authors: lim ac. Biochim Biophys Acta. 2014 Jul;1843(7):1325-38. doi: 10.1016/j.bbamcr.2014.03.024. Epub 2014 Apr 2. Biochim Biophys Acta. 2014. PMID: 24703881 Free article.

7

Membrane cholesterol modulates STEAP2 conformation during dynamic intracellular trafficking processes leading to broad subcellular distribution.

Hasegawa H, Li C, Alba BM, Penny DM, Xia Z, Dayao MR, Li P, Zhang J, Zhou J, Lim D, Murawsky CM, Lim AC. Hasegawa H, et al. Among authors: lim d, lim ac. Exp Cell Res. 2018 Sep 15;370(2):208-226. doi: 10.1016/j.yexcr.2018.06.022. Epub 2018 Jun 27. Exp Cell Res. 2018. PMID: 29940176

8

Auto-induction of Pichia pastoris AOX1 promoter for membrane protein expression.

Lee JY, Chen H, Liu A, Alba BM, Lim AC. Lee JY, et al. Among authors: lim ac. Protein Expr Purif. 2017 Sep;137:7-12. doi: 10.1016/j.pep.2017.06.006. Epub 2017 Jun 13. Protein Expr Purif. 2017. PMID: 28619526

9

Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.

Sudom A, Talreja S, Danao J, Bragg E, Kegel R, Min X, Richardson J, Zhang Z, Sharkov N, Marcora E, Thibault S, Bradley J, Wood S, Lim AC, Chen H, Wang S, Foltz IN, Sambashivan S, Wang Z. Sudom A, et al. Among authors: lim ac. J Biol Chem. 2018 Aug 10;293(32):12634-12646. doi: 10.1074/jbc.RA118.002352. Epub 2018 May 24. J Biol Chem. 2018. PMID: 29794134 Free PMC article.

10

Mutation in IL36RN impairs the processing and regulatory function of the interleukin-36-receptor antagonist and is associated with DITRA syndrome.

Bal E, Lim AC, Shen M, Douangpanya J, Madrange M, Gazah R, Tauber M, Beghdadi W, Casanova JL, Bourrat E, Bachelez H, Towne JE, Smahi A. Bal E, et al. Among authors: lim ac. Exp Dermatol. 2019 Oct;28(10):1114-1117. doi: 10.1111/exd.13387. Epub 2017 Oct 26. Exp Dermatol. 2019. PMID: 28603914

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